Results 41 to 50 of about 1,998,502 (315)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A Tighter Bound for the Determinization of Visibly Pushdown Automata
, 2009 Visibly pushdown automata (VPA), introduced by Alur and Madhusuan in 2004, is a subclass of pushdown automata whose stack behavior is completely determined by the input symbol according to a fixed partition of the input alphabet.
Van Tang, Nguyen
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
‘LEGIS ACTIO SACRAMENTO IN REM’ AS A RITUAL
Zeszyty PrawniczeA ritual can be characterised as a form of conduct based on traditional and established rules. The basic purpose of its use is to confirm the validity of a particular action.
Marek Novák
doaj +1 more source
SYNTHESIS AS A PSYCHOLOGICAL METHOD: EVIDENCE OF USING THE SEMANTIC DIFFERENTIAL METHOD
Russian Journal of Education and Psychology, 2019 The purpose of the research is a psychological comprehension оf the conceptual and formal aspects of methodology. This paper presents a theoretical analysis of the integral paradigm and synthesis as used in psychology. It dwells upon a formal methodology
Tatyana Ivanovna Ray
doaj +1 more source
The 19th entury iron architecture of industrial buildings. A formal and constructive comparison between two case studies [PDF]
, 2018 The paper analyzes the features of the 19th century industrial architecture and the application of metallic structures combined with formal and architectural expressions that frequently concealed or mitigated their presence.
Bosch González, Montserrat +1 more
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
‘The Action of the Brain’. Machine Models and Adaptive Functions in Turing and Ashby [PDF]
, 2018 Given the personal acquaintance between Alan M. Turing and W. Ross Ashby and the partial proximity of their research fields, a comparative view of Turing’s and Ashby’s work on modelling “the action of the brain” (letter from Turing to Ashby, 1946) will ...
Greif, Hajo
core
Symbolic models for nonlinear control systems affected by disturbances
, 2012 In the last few years there has been a growing interest in the use of symbolic models for the formal verification and control design of purely continuous or hybrid systems.
Borri, Alessandro +2 more
core +1 more source
Dispersionless integrable systems in 3D and Einstein-Weyl geometry [PDF]
, 2013 For several classes of second order dispersionless PDEs, we show that the symbols of their formal linearizations define conformal structures which must be Einstein-Weyl in 3D (or self-dual in 4D) if and only if the PDE is integrable by the method of ...
Ferapontov, Eugene, Kruglikov, Boris
core +2 more sources