Results 81 to 90 of about 14,483 (309)

A hybrid symbolic-numerical approach to the center-focus problem

, 2017
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)We propose a new hybrid symbolic-numerical approach to the center-focus problem.
Hauenstein, Jonathan D., Claudio Pessoa, Adam Mahdi, Jonathan D. Hauenstein, Mahdi, Adam, Pessoa, Claudio, Pessoa, Claudio [UNESP]   +6 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Reliable scalable symbolic computation: the design of SymGridPar2 [PDF]

, 2013
Symbolic computation is an important area of both Mathematics and Computer Science, with many large computations that would benefit from parallel execution.
P. Maier, Stewart, Robert; id_orcid, Trinder, Philip William, Maier, Patrick, P.W. Trinder, Trinder, Phil W, Stewart, R., Phil Trinder, Trinder, P. W., Patrick Maier, R. Stewart, Rob Stewart, Trinder, P.W., Maier, P., Stewart, Robert   +14 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

9th International Symposium on Symbolic Computation in Software Science (SCSS 2021) : short and work-in-progress papers : RISC Report Series, 21-16

, 2021
This collection contains short and work-in-progress papers presented at the 9th International Symposium on Symbolic Computation in Software Science, SCSS ...

core   +2 more sources

The single-mass variable flavor number scheme at three-loop order

Journal of High Energy Physics
The matching relations in the unpolarized and polarized variable flavor number scheme at three-loop order are presented in the single-mass case. They describe the process of massive quarks becoming light at large virtualities Q 2.
J. Ablinger, A. Behring, J. Blümlein, A. De Freitas, A. von Manteuffel, C. Schneider, K. Schönwald   +6 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Discriminative Structure Learning of Bayesian Network Classifiers from Training Dataset and Testing Instance

Entropy, 2019
Over recent decades, the rapid growth in data makes ever more urgent the quest for highly scalable Bayesian networks that have better classification performance and expressivity (that is, capacity to respectively describe dependence relationships between
LiMin Wang, Yang Liu, Musa Mammadov, MingHui Sun, Sikai Qi   +4 more
doaj   +1 more source

Computation of dilated Kronecker coefficients.

, 2017
The computation of Kronecker coefficients is a challenging problem with a variety of applications. In this paper we present an approach based on methods from symplectic geometry and residue calculus.
Walter, M, Vergne, M, Baldoni, M, Walter M., Vergne M., Baldoni Maria   +5 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source