Results 41 to 50 of about 458,046 (300)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Symbolizm architektoniczny: polityka wyrażona w kamieniu
Historia i Polityka, 2016 Architecture is studied as a system of signs – symbols which are significant for understanding the essence and specific features of politics. We investigate how the architectural forms and images influence the political outlook of the person in the ...
Natalia Khoma
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Odyssey of the Eyes Intermediate Level [PDF]
, 2003 The purpose of this resource is to familiarize students with modeling as it relates to remote sensing and digitized images. Students will use the symbolic map created in the beginning activity to produce a digitized image and begin to see why ground ...
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Image and Text, Relationships and Differences – The Role of Language in the Visual Fields
ESPESThe paper explores the relationships and distinctions between pictorial and linguistic symbolic systems. It addresses the issue of the interplay between these media and symbolic systems. The paper explains why we cannot speak of any “pure” approaches and
Kateřina Dytrtová
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Nordic Journal of Media Studies, 2021 In this article, I investigate how recipients make sense of images that show symbolic actions by environmental activists during two recent United Nations Climate Change Conferences.
Wozniak Antal
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The Theory of Symbolic Image in Byzantine Theology of the VI-VIIth centuries
Волинський благовісник, 2017 The article is devoted to the philosophical and aesthetic analysis of the theory of symbolic image in the theological texts of Pseudo-Dionysius the Areopagite and Maximus the Confessor.
Victoria Golovey
doaj +1 more source