Results 221 to 230 of about 17,106 (295)

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

Integrating machine learning and symbolic regression for predicting damage initiation in hybrid FRP bolted connections. [PDF]

Sci Rep
Sorour SS, Saleh CA, Shazly M.
europepmc   +1 more source

GPTIPS: Genetic Programming and Symbolic Regression for Matlab

GPTIPS is a free, open source MATLAB toolbox for performing genetic programming and symbolic regression. GPTIPS provides a simple, easy to use framework to allow scientists and engineers to automatically develop compact, accurate data driven non-linear ...
Searson DP
core  

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

Advanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan, Ruimin Chang, Meng Zhang, Qian Dong, Guanxiong Zhang, Xiang Chen, Mingliang Chen, Lixia Lu, Xiaowei Liang, Yeye Guo, Juan Su   +10 more
wiley   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

Symbolic regression for strength prediction of eccentrically loaded concrete-filled steel tubular columns. [PDF]

Sci Rep
Megahed K.
europepmc   +1 more source

AI-driven methodology to develop (hybrid) steady-state and dynamic process models

reservedMany chemical engineering applications face the challenge of building accurate and interpretable models from sparse, noisy, and costly data. This need arises especially in early-stage process design or when experimenting with novel unit equipment,
ROSSI, LORENZO
core  

Liquid Metals in Radio Frequency Applications: A Review of Physics, Manufacturing, and Emerging Technologies

Advanced Electronic Materials, EarlyView.
This paper reviews the physics of liquid metals in RF devices, including the influence of mechanical strain on resonance as well as fabrication methods and strategies for designing tunable and strain‐tolerant inductors, capacitors, and antennas.
Md Saifur Rahman, William J. Scheideler
wiley   +1 more source

STM-based symbolic regression for strength prediction of RC deep beams and corbels. [PDF]

Sci Rep
Megahed K.
europepmc   +1 more source

Simple descriptor derived from symbolic regression accelerating the discovery of new perovskite catalysts. [PDF]

Nat Commun, 2020
Weng B, Song Z, Zhu R, Yan Q, Sun Q, Grice CG, Yan Y, Yin WJ.   +7 more
europepmc   +1 more source