Results 41 to 50 of about 1,980,475 (297)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Geomorphism, Archetypes and Symbols in Architecture
Agathón, 2017 This paper is a revision with updating of an essay on the theme Nature and Architecture, published in 1999. Here, with the support of other disciplines, there are some similarities between natural forms and architectural forms.
Paolo Portoghesi
doaj +1 more source
Symbol complexity and symbol identification with rotated symbols
Acta Psychologica, 1983 Abstract Previous studies of the identification of rotated symbols have been restricted to either alphanumeric characters or symbols designed to be similar in complexity and type to alphanumerics. These researches have found identification response times to be independent of the magnitude of a symbol's angular displacement from a standard upright ...
openaire +2 more sources
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Discrete Moyal-type representations for a spin [PDF]
, 2000 In Moyal’s formulation of quantum mechanics, a quantum spin s is described in terms of continuous symbols, i.e., by smooth functions on a two-dimensional sphere.
A. Perelomov +18 more
core +3 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
On universal modular symbols [PDF]
, 2014 We clarify the relationship between works of Lee-Szczarba and Ash-Rudolph on the homology of the Steinberg module of a linear Tits building. This yields a simple proof of the Solomon-Tits theorem in this special case.
Kahn, Bruno, Sun, Fei
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
SYMBOLISM AND ISLAMIC VALUES IN STUDENTS’ REOG STAGE AT MUHARAM CELEBRATION
Jurnal Dakwah Risalah, 2021 Signs, symbols, and meanings are important elements in human interaction. This research aims to reveal how the signs, symbols, and meanings related and can be used to describe the relationship among students in Reog culture staging.
Muslih Aris Handayani
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source