Results 41 to 50 of about 727,533 (258)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Exact Solutions of the Symmetric Regularized Long Wave Equation and the Klein-Gordon-Zakharov Equations

Abstract and Applied Analysis, 2014
We study two nonlinear partial differential equations, namely, the symmetric regularized long wave equation and the Klein-Gordon-Zakharov equations. The Lie symmetry approach along with the simplest equation and exp-function methods are used to obtain ...
Isaiah Elvis Mhlanga, Chaudry Masood Khalique   +1 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Revival and Multiplatform Presentation of Forgotten Religious Heritage Sites in the Project Named “Sacred Past”

Digital Presentation and Preservation of Cultural and Scientific Heritage, 2023
The objective of the paper is to shed light on the importance of the digital presentation of religious heritage and present the multimedia documentation of a chapel developed within the “Oltári Múlt” (“Sacred Past”, in Hungarian) project.
Gizella Börcsök, Róbert Z. Nagy, Krisztián Vollmuth, Zsolt L. Márkus, András J. Molnár, György Szántó, Tibor Szkaliczki, Miklós Veres, Zsolt Weisz   +8 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

A (3+1)-dimensional generalized BKP-Boussinesq equation: Lie group approach

Results in Physics, 2019
A (3+1)-D generalized B-type KP-Boussinesq equation, which was recently formulated in the literature, is investigated here from Lie group standpoint. A solution is obtained by Lie symmetry reductions and direct integration in terms of incomplete elliptic
Chaudry Masood Khalique, Letlhogonolo Daddy Moleleki   +1 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Acknowledgement to Reviewers of Symmetry in 2015

, 2016
The editors of Symmetry would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015.
Symmetry Editorial Office
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Lie Group Classification of a Generalized Lane-Emden Type System in Two Dimensions

Journal of Applied Mathematics, 2012
The aim of this work is to perform a complete Lie symmetry classification of a generalized Lane-Emden type system in two dimensions which models many physical phenomena in biological and physical sciences.
Motlatsi Molati, Chaudry Masood Khalique
doaj   +1 more source