Results 91 to 100 of about 702,712 (350)

The Effect of the Vestibular System on Bone Regeneration: a Look at the Vestibular ‎System Beyond its Classical Role [PDF]

Journal of Paramedical Science and Rehabilitation
Purpose: The purpose of this study is to investigate the effect of the vestibular system on the bone formation process and the possible path of this effect.
S khakzand, Y Lotfi, M Shabani
doaj   +1 more source

Rapid severe hypertension and organ damage in two‐kidney two‐clip rats produced by different sizes of clips

Animal Models and Experimental Medicine, EarlyView.
Blood pressure increases immediately when the 2K2C rats (made with 0.3, 0.25, and 0.2 mm U‐shaped clips) regain consciousness from anesthesia. 100% of the rats develop hypertension on the day of 2K2C surgery. Blood pressure continues to rise, resulting in severe hypertension and organ damage to the brain, heart, aorta, and kidneys at 1, 2, 4, and 6 ...
Jia‐Sheng Tian, Qi‐Sheng Ling, Yu‐Chen Wei, Dao‐Xin Wang, Chao‐Yu Miao   +4 more
wiley   +1 more source

Oxidative Stress in the Brain Causes Hypertension via Sympathoexcitation

Frontiers in Physiology, 2012
Activation of the sympathetic nervous system has an important role in the pathogenesis of　hypertension, and is determined by the brain. Previous many studies have demonstrated that oxidative stress, mainly produced by angiotensin II type 1 (AT1) receptor
Takuya eKishi, Yoshitaka eHirooka
doaj   +1 more source

Cistanche tubulosa improves peripheral neuropathy in MPTP‐induced PD mice based on regulation of m6A methylation

Animal Models and Experimental Medicine, EarlyView.
At steady state, DRG ensures low‐level expression of TH+ neurons under the protection of AKT. However, the DRG level of PD mouse model under MPTP toxicity increased significantly, and the expression of IL‐6 and CASP3 increased. This process was accompanied by the occurrence of m6A demethylation, with a significant increase in FTO as the main ...
Yatan Li, Wei Jia, Junhua Hu, Borui Zhang, Xinxin Qi, Jianhua Yang, Xinling Yang   +6 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Strategies for optimization of hypoglycemia rat models

Animal Models and Experimental Medicine, EarlyView.
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher, Eason Kong Qi Zheng, Rayneshia Elaura Raymond, Ye Zhen Jie, Christina Gertrude Yap   +4 more
wiley   +1 more source

Guideline for the application of heart rate and heart rate variability in occupational medicine and occupational health science

Journal of Occupational Medicine and Toxicology
This updated guideline replaces the “Guideline for the application of heart rate and heart rate variability in occupational medicine and occupational health science” first published in 2014.
Stefan Sammito, Beatrice Thielmann, Andre Klussmann, Andreas Deußen, Klaus-Michael Braumann, Irina Böckelmann   +5 more
doaj   +1 more source

THE PARTICIPATION OF CATECHOLAMINES IN THE PATHOGENESIS OF DIABETIC CARDIOMYOPATHY

Медицина в Кузбассе, 2020
Under normal conditions, the sympathetic nervous system, through its main mediators (catecholamines) plays an important role in the functioning of the cardiovascular system.
Алексей Михайлович Чаулин, Юлия Владимировна Григорьева, Дмитрий Викторович Дупляков   +2 more
doaj  

Long-Term Exposure to Concentrated Ambient PM2.5 Increases Mouse Blood Pressure through Abnormal Activation of the Sympathetic Nervous System: A Role for Hypothalamic Inflammation

Environmental Health Perspectives, 2013
Background: Exposure to particulate matter ≤ 2.5 μm in diameter (PM2.5) increases blood pressure (BP) in humans and animal models. Abnormal activation of the sympathetic nervous system may have a role in the acute BP response to PM2.5 exposure.
Z. Ying, Xiaohua Xu, Yuntao Bai, Jixin Zhong, Minjie Chen, Yijia Liang, Jinzhuo Zhao, Dongyao Liu, M. Morishita, Qinghua Sun, C. Spino, Robert D. Brook, Jack R. Harkema, Sanjay Rajagopalan   +13 more
semanticscholar   +1 more source

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

Animal Models and Experimental Medicine, EarlyView.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang, Wenlu Ma, Wei Wu, Yujuan Fu, Hui Li   +4 more
wiley   +1 more source