Results 131 to 140 of about 311,363 (330)
Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions
Cancer Nexus, EarlyView.ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley +1 more source
MIND-BODY RESPONSE AND NEUROPHYSIOLOGICAL CHANGES DURING STRESS AND MEDITATION: CENTRAL ROLE OF HOMEOSTASIS [PDF]
, 2014 Stress profoundly impacts quality of life and may lead to various diseases and conditions. Understanding the underlying physiological and neurological processes that take place during stress and meditation techniques may be critical for effectively ...
Barnes, Vernon A. +2 more
core
Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins
Developmental Dynamics, EarlyView.Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming +14 more
wiley +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Real-time imaging of the medullary circuitry involved in the generation of spontaneous muscle sympathetic nerve activity in awake human subjects [PDF]
, 2008 In order to understand the central neural processes involved in blood pressure regulation we recorded muscle sympathetic nerve activity (MSNA) via a tungsten microelectrode in the common peroneal nerve while performing functional Magnetic Resonance ...
Luke Henderson, Vaughan Macefield
core +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou +7 more
wiley +1 more source
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source
The Role of Central Oxytocin in Autonomic Regulation
Journal of Physiological InvestigationOxytocin (OXT), a neuropeptide originating from the hypothalamus and traditionally associated with peripheral functions in parturition and lactation, has emerged as a pivotal player in the central regulation of the autonomic nervous system (ANS).
Sheng-Feng Tsai, Yu-Min Kuo
doaj +1 more source
The Sympathetic Nervous System in Obstetric and Gynaecological Practice [PDF]
, 1949 Albert Davis
openalex +1 more source