Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
The role of the autonomic nervous system in polycystic ovary syndrome
This article reviewed the relationship between the autonomic nervous system and the development of polycystic ovary syndrome (PCOS). PCOS is the most common reproductive endocrine disorder among women of reproductive age.
Yue Yu +7 more
doaj +1 more source
Sympathetic hyperactivity in patients with hypertension: pathogenesis and treatment. Part II
The second part of the review considers different classes of drugs affecting blood pressure in increased activity of the sympathetic nervous system. Additional possibilities are discussed on how to reduce the negative effect of sympathetic hyperactivity ...
A. S. Safaryan, D. V. Nebieridze
doaj +1 more source
Neural regulation of cardiovascular response to exercise: role of central command and peripheral afferents [PDF]
During dynamic exercise, mechanisms controlling the cardiovascular apparatus operate to provide adequate oxygen to fulfill metabolic demand of exercising muscles and to guarantee metabolic end-products washout.
Crisafulli, A +5 more
core +4 more sources
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Autonomic Nervous System in the Control of Energy Balance and Body Weight: Personal Contributions
The prevalence of obesity is increasing in the industrialized world, so that the World Health Organization considers obesity as a “pandemia” in rich populations.
G. Messina +6 more
doaj +1 more source
Elevated blood pressure, heart rate and body temperature in mice lacking the XL alpha s protein of the Gnas locus is due to increased sympathetic tone [PDF]
NEW FINDINGS: What is the central question of this study? Previously, we showed that Gnasxl knock-out mice are lean and hypermetabolic, with increased sympathetic stimulation of adipose tissue.
Antonius Plagge +5 more
core +1 more source
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song +6 more
wiley +1 more source
Autonomic dysbalancy correction in patients with the metabolic syndrome with the physical rehabilitation methods [PDF]
The results of influence of the author program of physical rehabilitation are rotined on activity of sympathetic and parasympathetic link of the vegetative nervous system.
Tershak N.N.
doaj
Background Use of the antipsychotic drug olanzapine by patients with schizophrenia is associated with autonomic nervous system (ANS) dysfunction.
Saki Hattori +12 more
doaj +1 more source

