Results 161 to 170 of about 3,862 (291)

Persistence with medical glaucoma therapy in newly diagnosed patients. [PDF]

Med Hypothesis Discov Innov Ophthalmol
Menino J, Camacho P, Coelho A.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

A study of pupil shape and size by sympathomimetics

Indian Journal of Ophthalmology, 1973
Jain I, Nagpal K, Sharma P
doaj  

Risk of retinal artery occlusion in patients with primary open-angle glaucoma: a retrospective cohort study. [PDF]

Int J Retina Vitreous
Shemesh N, Nitzan I, Kubovsky S, Shalmov T, Eshel Y, Erdinest N, Lavy I, Levy J.   +7 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Maternal Primary Sjögren's Syndrome Complicated by Irreversible Fetal Third-Degree Congenital Heart Block: A Case Report From Nepal. [PDF]

Clin Case Rep
Shah P, Jaiswal P, Adhikari P, Jaiswal SK, Parajuli K.   +4 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Unexpected Fetal Supraventricular Tachycardia Temporally Associated With Maternal Antihistamine Use: A Case Report. [PDF]

Case Rep Obstet Gynecol
Kermani KR, Rajaei S, Goudarzi RM, Abdi N.   +3 more
europepmc   +1 more source

Therapeutic potential of small molecules that block receptor‐induced Kv7/M‐current suppression in neuroprotection, seizures, and pain

British Journal of Pharmacology, EarlyView.
Receptor‐induced Kv7/M‐current suppression increases neuronal activity and contributes to pathology of several conditions. A new class of Kv7 modulators identified in this study attenuates M‐current suppression and shows therapeutic effects. Abstract Background and Purpose Neuronal Kv7 channels generate low voltage–gated potassium currents known as the
Young Woo Kim, Pavan Kumar Behara, Lamees Alhassen, Cindy Wong, Olivier Civelli, Naoto Hoshi   +5 more
wiley   +1 more source

Working group summary of the 2023 full update of the Finnish national guidelines for paediatric lower respiratory tract infections. [PDF]

Acta Paediatr
Backman K, Helminen M, Kekäläinen E, Mikkola I, Nieminen T, Nuolivirta K, Peltola V, Seuri R, Walle SM, Ruuska-Loewald T.   +9 more
europepmc   +1 more source