Results 41 to 50 of about 47,169 (292)

Amino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis

open access: yesAdvanced Science, EarlyView.
This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo   +15 more
wiley   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He   +11 more
wiley   +1 more source

Enhancing Sensitivity across Scales with Highly Sensitive Hall Effect‐Based Auxetic Tactile Sensors

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a tactile sensor based on hall‐effect sensors with an auxetic structure, called Hall effect‐based auxetic tactile sensor (HEATS), is proposed. The change in magnetism resulting from the deformation of the auxetic structure is utilized for sensing.
Youngheon Yun   +6 more
wiley   +1 more source

A arte do corpo relacional: do espelho-tátil ao corpo virtual

open access: yesGaláxia, 2016
Mirror neurons are specialized neurons which echo the movements perceived in another's body in incipient movements in one's own body, in a kind of involuntary kinesthetic empathy. Their discovery has given rise to a far-reaching reassessment in cognitive
Briam Massumi
doaj   +1 more source

Sympathy for t-PA [PDF]

open access: yesThe Journal of Experimental Medicine, 2006
Tissue plasminogen activator (t-PA), a protease released by vascular endothelial cells, keeps blood flowing freely by busting up clots. But t-PA is also produced by sympathetic nerve endings where, according to Schaefer et al.
openaire   +2 more sources

Addressing Anemia in High‐Altitude Populations: Global Impact, Prevalence, Challenges, and Potential Solutions

open access: yesAmerican Journal of Hematology, EarlyView.
Key challenges in diagnosing anemia in high‐altitude populations include variability in hemoglobin (Hb) concentration, associated pathological conditions, altitude‐induced plasma volume changes, and environmental factors such as contamination and nutrition.
Ayoub Boulares   +11 more
wiley   +1 more source

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote   +9 more
wiley   +1 more source

Pain as Yardstick: Jean Améry

open access: yesJournal of French and Francophone Philosophy, 2017
One of the best known and most widely accepted premises regarding the experience of pain and suffering is its singular, private nature. Pain’s violence isolates us from everything else, embedding us completely within our own suffering so that there is ...
Ilit Ferber
doaj   +1 more source

Sympathy–Antipathy in Daniel Deronda

open access: yes19, 2020
This article argues that, in her final novel, Daniel Deronda, Eliot uses her eponymous protagonist to simultaneously exemplify and problematize the type of sympathy she had championed from the 1850s. Sympathetic affinity in the novel works like original ‘
Carolyn Burdett
doaj   +2 more sources

Culture, Connection and Care: The Role of Institutional Justice Capital for Enhancing the Wellbeing of Aboriginal and Torres Strait Islander Children in Out‐Of‐Home Care

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Ensuring that Aboriginal and Torres Strait Islander children removed from their families by child protection services remain connected to their kin, Country and culture is a priority to begin to redress the intergenerational trauma and harm caused by colonisation.
Sharynne Hamilton   +9 more
wiley   +1 more source

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