Results 131 to 140 of about 34,958 (256)

Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes [PDF]

, 2015
Acknowledgements The Rowett Institute of Nutrition and Health (University of Aberdeen) receives financial support from the Scottish Government Rural and Environmental Sciences and Analytical Services (RESAS).
Bernalier-Donadille, Annick, Browne, Hilary P., Duncan, Sylvia H., Flint, Harry J., Harris, Hugh M. B., Lawley, Trevor D., Martin, Jennifer C., O'Toole, Paul W., Scott, Karen P., Sheridan, Paul O.   +9 more
core   +2 more sources

Sodium Iodide Symporter (NIS) and Thyroid

HORMONES, 2002
idase (TPO) and incorporation into tyrosyl residues along the thyroglobulin (Tg) backbone. The thyroid hormones T3 and T4 are synthesized by coupling of two iodotyrosine residues and stored in the colloid. All of these steps are stimulated by pituitary-derived thyroid stimulating hormone (TSH), which interacts with the TSH receptor at the basolateral ...
Christine, Spitzweg, John C, Morris
openaire   +2 more sources

Transition metal ion FRET uncovers K+ regulation of a neurotransmitter/sodium symporter

Nature Communications, 2016
Neurotransmitter/sodium symporters (NSSs) are responsible for Na+-dependent reuptake of neurotransmitters and represent key targets for antidepressants and psychostimulants.
Christian B. Billesbølle, J. S. Mortensen, Azmat Sohail, S. Schmidt, Lei Shi, H. Sitte, U. Gether, C. Loland   +7 more
semanticscholar   +1 more source

TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells.

PLoS ONE, 2020
The sodium-iodide symporter (NIS) mediates transport of iodide across the basolateral membrane of thyroid cells. NIS expression in thyroid cancer (TC) cells allows the use of radioactive iodine (RAI) as a diagnostic and therapeutic tool, being RAI ...
Márcia Faria, Rita Domingues, Francisca Paixão, Maria João Bugalho, Paulo Matos, Ana Luísa Silva   +5 more
doaj   +1 more source

miRNA-106a directly targeting RARB associates with the expression of Na+/I− symporter in thyroid cancer by regulating MAPK signaling pathway

Journal of experimental & clinical cancer research : CR, 2016
BackgroundSerum miRNAs profiles between papillary thyroid carcinoma (PTC) patients with non-131I and 131I-avid lung metastases are differentially expressed.
Chen-tian Shen, Zhong-Ling Qiu, Hong-jun Song, Weijun Wei, Quan-Yong Luo   +4 more
semanticscholar   +1 more source

Tracking of dendritic cell migration into lymph nodes using molecular imaging with sodium iodide symporter and enhanced firefly luciferase genes

Scientific Reports, 2015
We sought to evaluate the feasibility of molecular imaging using the human sodium iodide symporter (hNIS) gene as a reporter, in addition to the enhanced firefly luciferase (effluc) gene, for tracking dendritic cell (DCs) migration in living mice.
H. Lee, S. Yoon, Thoudam Debraj Singh, Yoon Ju Choi, H. Lee, Ji Young Park, S. Jeong, Sang-Woo Lee, J. Ha, B. Ahn, Y. Jeon, Jaetae Lee   +11 more
semanticscholar   +1 more source

In vivo SPECT reporter gene imaging of regulatory T cells.

PLoS ONE, 2011
Regulatory T cells (Tregs) were identified several years ago and are key in controlling autoimmune diseases and limiting immune responses to foreign antigens, including alloantigens.
Ehsan Sharif-Paghaleh, Kavitha Sunassee, Richard Tavaré, Kulachelvy Ratnasothy, Alexander Koers, Niwa Ali, Rowa Alhabbab, Philip J Blower, Robert I Lechler, Lesley A Smyth, Gregory E Mullen, Giovanna Lombardi   +11 more
doaj   +1 more source

Identity of a Plasmodium lactate/H+ symporter structurally unrelated to human transporters

Nature Communications, 2015
Maintenance of a high glycolytic flow rate is critical for the rapid growth and virulence of malarial parasites. The parasites release two moles of lactic acid per mole of glucose as the anaerobic end product.
Binghua Wu, J. Rambow, Sinja Bock, Julia Holm-Bertelsen, Marie Wiechert, Alexandra Blancke Soares, T. Spielmann, E. Beitz   +7 more
semanticscholar   +1 more source

Radioactive Iodine Therapy and Glucose Tolerance

Cell Journal, 2017
Radioactive iodine therapy is commonly used as an adjuvant therapy in follicular and papillary thyroid carcinoma (PTC) and in the treatment of Graves’ disease (GD).
Roghaieh Samadi, Asghar Ghasemi, Babak Shafiei, Fereidoun Azizi   +3 more
doaj   +1 more source

Study on the Iodine 125 Uptake of H460 Lung Cancer Cell Line by Co-transfection with the Human Sodium/Iodide Symporter and the Human Thyroperoxidase [PDF]

, 2010
Background and objective Lung cancer harms people’s health or even lives severely. Especially, the therapy of non-small cell lung cancer (NSCLC) has not been obviously improved for many years.
Jian TAN, Lei LONG, Wei LI
core