Results 41 to 50 of about 34,958 (256)

Metadynamics simulations reveal a Na+ independent exiting path of galactose for the inward-facing conformation of vSGLT. [PDF]

PLoS Computational Biology, 2014
Sodium-Galactose Transporter (SGLT) is a secondary active symporter which accumulates sugars into cells by using the electrochemical gradient of Na+ across the membrane. Previous computational studies provided insights into the release process of the two
Ina Bisha, Alex Rodriguez, Alessandro Laio, Alessandra Magistrato   +3 more
doaj   +1 more source

Crystal structure of the plant symporter STP10 illuminates sugar uptake mechanism in monosaccharide transporter superfamily

Nature Communications, 2019
Plants are dependent on controlled sugar uptake for correct organ development and sugar storage, and apoplastic sugar depletion is a defense strategy against microbial infections like rust and mildew.
P. A. Paulsen, T. Custódio, B. P. Pedersen   +2 more
semanticscholar   +1 more source

Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]

, 2017
Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle, Afzal, Junaid, Aon, Miguel A, Chan, Angel, Foster, D. Brian, Guan, Yufan, Karakas, Mehmet Fatih, O\u27Rourke, Brian, Pomper, Martin, Rathmell, Jeffrey, Tsui, Benjamin, Vakrou, Styliani, Wahl, Richard, Woldemichael, Kirubel   +13 more
core   +2 more sources

Reporter gene-engineering of human induced pluripotent stem cells during differentiation renders in vivo traceable hepatocyte-like cells accessible

Stem Cell Research, 2019
Primary hepatocyte transplantation (HTx) is a safe cell therapy for patients with liver disease, but wider application is circumvented by poor cell engraftment due to limitations in hepatocyte quality and transplantation strategies. Hepatocyte-like cells
Candice Ashmore-Harris, Samuel JI Blackford, Benjamin Grimsdell, Ewelina Kurtys, Marlies C Glatz, Tamir S Rashid, Gilbert O Fruhwirth   +6 more
doaj   +1 more source

Mutational analysis of the respiratory nitrate transporter NarK2 of Mycobacterium tuberculosis. [PDF]

PLoS ONE, 2012
Mycobacterium tuberculosis induces nitrate reductase activity in response to decreasing oxygen levels. This is due to regulation of both the transcription and the activity of the nitrate transporter NarK2.
Michelle M Giffin, Ronald W Raab, Melissa Morganstern, Charles D Sohaskey   +3 more
doaj   +1 more source

Genetic Factors That Might Lead to Different Responses in Individuals Exposed to Perchlorate [PDF]

, 2005
Perchlorate has been detected in groundwater in many parts of the United States, and recent detection in vegetable and dairy food products indicates that contamination by perchlorate is more widespread than previously thought.
Fowler, Bruce A., Murray, H. Edward, Scinicariello, Franco, Smith, Lester, Wilbur, Sharon   +4 more
core   +2 more sources

Iodine status in Turkish populations and exposure to iodide uptake inhibitors. [PDF]

PLoS ONE, 2014
Perchlorate, nitrate, and thiocyanate are competitive inhibitors of the sodium iodide symporter of the thyroid membrane. These inhibitors can decrease iodine uptake by the symporter into the thyroid gland and may disrupt thyroid function.
Aysel Ozpinar, Fahrettin Kelestimur, Yildiran Songur, Ozge Can, Liza Valentin, Kathleen Caldwell, Ender Arikan, Ibrahim Unsal, Mustafa Serteser, Tamer Inal, Yigit Erdemgil, Abdurrahman Coskun, Nadi Bakirci, Ozlem Sezgin, Ben Blount   +14 more
doaj   +1 more source

Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters

Cell Research, 2017
The Escherichia coli uracil:proton symporter UraA is a prototypical member of the nucleobase/ascorbate transporter (NAT) or nucleobase/cation symporter 2 (NCS2) family, which corresponds to the human solute carrier family SLC23.
Xinzhe Yu, Guanghui Yang, Chuangye Yan, Javier L. Baylon, Jing Jiang, H. Fan, G. Lu, K. Hasegawa, H. Okumura, Tingliang Wang, E. Tajkhorshid, Shuo Li, N. Yan   +12 more
semanticscholar   +1 more source

Saccharomyces cerevisiae glycerol/H⁺ symporter Stl1p is essential for cold/near-freeze and freeze stress adaptation. A simple recipe with high biotechnological potential is given

Microbial Cell Factories, 2010
Background Freezing is an increasingly important means of preservation and storage of microbial strains used for many types of industrial applications including food processing. However, the yeast mechanisms of tolerance and sensitivity to freeze or near-
Ferreira Célia, Lucas Cândida, Lima Ana, Tulha Joana   +3 more
doaj   +1 more source

Effect of sugar transporter on galactose utilization in Streptococcus thermophilus

Frontiers in Microbiology, 2023
IntroductionStreptococcus thermophilus is a traditional starter for dairy products. The lactose rich in milk is the main carbon source for the growth of S. thermophilus. However, the utilization of galactose by S.
Jiancun Zhao, Yan Liang, Yan Liang, Susu Zhang, Zhenshang Xu, Zhenshang Xu   +5 more
doaj   +1 more source