Results 101 to 110 of about 2,284,312 (360)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Effects of Mini-Basketball Training Program on Executive Functions and Core Symptoms among Preschool Children with Autism Spectrum Disorders [PDF]

, 2020
Jingui Wang, Kelong Cai, Zhimei Liu, Fabian Herold, Liye Zou, Lina Zhu, Xuan Xiong, Aiguo Chen   +7 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Injectable, reversibly thermoresponsive captopril-laden hydrogel for the local treatment of sensory loss in diabetic neuropathy

Scientific Reports
A major and irreversible complication of diabetes is diabetic peripheral neuropathy (DPN), which can lead to significant disability and decreased quality of life.
Amit Chandra Das, James M. Nichols, Caitlin V. Crelli, Lu Liu, Riddhi Vichare, Hoang Vu Pham, Caitlyn M. Gaffney, Fisher R. Cherry, Peter M. Grace, Andrew J. Shepherd, Jelena M. Janjic   +10 more
doaj   +1 more source

Effectiveness of physical, psychological, social, and spiritual intervention in breast cancer survivors: An integrative review

Asia-Pacific Journal of Oncology Nursing, 2016
Factors affecting the health outcomes of cancer patients have gained extensive research attention considering the increasing number and prolonged longevity of cancer survivors.
Di Wei, Xiang-Yu Liu, Yong-Yi Chen, Xin Zhou, Hui-Ping Hu   +4 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Akut Tonsillofarenjitli Çocuklarda Beta Hemolitik Streptokok Varlığını Gösteren Belirti ve Bulguların Değerlendirilmesi

Ankara Medical Journal, 2019
Amaç: Streptokoksik tonsillofarenjitte erken ve uygun antibiyotik tedavisi semptomları azaltıp bulaşıcılık süresinin kısaltılmasında, akut glomerülonefrit ve akut romatizmal ateş gibi poststreptokokkal komplikasyonların önlenmesinde önemlidir.
Şamil Hızlı, Filiz Meryem Altay
doaj   +1 more source

Rescoring the NIH chronic prostatitis symptom index: nothing new. [PDF]

, 2009
The National Institutes of Health-chronic prostatitis symptom index (NIH-CPSI) is a commonly used 13-item questionnaire for the assessment of symptom severity in men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
Calhoun, EA, Clemens, JQ, Crowley, EM, Dunn, RL, Landis, JR, Litwin, MS, McNaughton-Collins, M   +6 more
core