Results 101 to 110 of about 1,397,203 (301)

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Exploring the experiences of cancer survivors with a mobile survivorship care plan application: a mixed-methods study

Cancer Survivorship Research & Care
Background Survivorship care plans (SCPs) aid cancer survivors in transitioning from active treatment to long-term survivorship. Mobile health approaches to survivorship could enhance the effectiveness of SCPs.
Shalet James, Maria S. Rangwala, Gautam G. Rao, Nicolette M. McGeorge, Amber S. Kleckner   +4 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Factors Associated With Symptom Relief in End-of-Life Care in Residential Care Homes : A National Register-Based Study

, 2018
Context: Residential care homes (RCHs) are a common place of death. Previous studies have reported a high prevalence of symptoms such as pain and shortness of breath among residents in the last week of life.
Årestedt, Kristofer,, Carl-Johan Fürst, Lindqvist, O, Fürst, Carl Johan,, Brannstrom, M, Lindqvist, Olav,, Andersson, Sofia, Andersson, S., Andersson, Sofia,, Andersson, S, Arestedt, K., Arestedt, K, Kristofer Årestedt, Lindqvist, Olav, Sofia Andersson, Lindqvist, O., Furst, C. J., Olav Lindqvist, Furst, Carl-Johan,, Margareta Brännström, Brännström, Margareta,, Fürst, Carl Johan, Furst, C-J, Brännström, Margareta, Lund University., Årestedt, Kristofer   +25 more
core   +1 more source

Developing a fit-for-purpose composite symptom score as a symptom burden endpoint for clinical trials in patients with malignant pleural mesothelioma

Scientific Reports
We developed a composite symptom score (CSS) representing disease-related symptom burden over time in patients with malignant pleural mesothelioma (MPM).
Charles S. Cleeland, Karen N. Keating, Brian Cuffel, Cem Elbi, Jonathan M. Siegel, Christoph Gerlinger, Tara Symonds, Jeff A. Sloan, Amylou C. Dueck, Andrew Bottomley, Xin Shelley Wang, Loretta A. Williams, Tito R. Mendoza   +12 more
doaj   +1 more source

Facilitators and barriers for return to work among patients with post-COVID-19 condition: a qualitative interview study

Scandinavian Journal of Primary Health Care
Background Post COVID-19 condition (PCC) can have long-lasting adverse effects, including impacts on work ability. This study explores the facilitators and barriers in the return-to-work (RTW) process.Design and methods Conducted in spring 2023 at the ...
Aleksandra Sulg, Aki Vuokko, Kirsi Kvarnström, Mikko Varonen, Antti Malmivaara, Jari Arokoski, Helena Liira   +6 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Patient‐Reported Outcomes for Patients With Metastatic NSCLC Treated at an Academic Medical Center, 2017–2021

Cancer Medicine
Background Understanding the symptom burden experienced by patients with cancer can enable appropriate supportive care. Our aim was to describe patient‐reported outcomes (PROs) for patients with metastatic NSCLC initiating first‐line (1L) systemic ...
Loretta A. Williams, Cai Xu, Darcy A. Ponce, Qiuling Shi, Melissa L. Santorelli, Thomas Burke, Mehmet Altan   +6 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Recruitment and retention of clinical trial participants: understanding motivations of patients with chronic pain and other populations

Frontiers in Pain Research
This paper aims to present and discuss the issues, challenges, and strategies related to recruitment and retention in clinical trials involving participants with chronic pain.
Joyce K. Anastasi, Bernadette Capili, Margaret Norton, Margaret Norton, Donald J. McMahon, Karen Marder   +5 more
doaj   +1 more source