Results 131 to 140 of about 187,009 (324)

Effects of hippocampal overexpression of LINGO-1 on learning and memory abilities and Spinophilin+ dendritic spines in different hippocampal subregions of mice

open access: yes陆军军医大学学报
Objective To investigate the effects of adenovirus-associated virus (AAV)-mediated overexpression of LINGO-1 in the hippocampus on spatial learning and memory abilities, as well as the volume and Spinophilin+ dendritic spines of different subregions ...
WANG Shun, JIANG Lin, HE Qi
doaj   +1 more source

Electrical Stimulation Therapy – Dedicated to the Perfect Plastic Repair

open access: yesAdvanced Science, EarlyView.
This review discusses various types of electrical stimulation sources and materials, delving into the roles and mechanisms of electrical stimulation therapy in plastic surgery for tissue repair. This work broadens the clinical perspective of electrical stimulation, covering diverse repair needs from bone to soft tissues, and provides insights into ...
Kexin Deng   +8 more
wiley   +1 more source

Leaky Synapses [PDF]

open access: yesNeuron, 1999
Nicoll, Roger A., Malenka, Robert C.
openaire   +2 more sources

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

open access: yesAdvanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du   +13 more
wiley   +1 more source

Projections from thalamic nucleus reuniens to hippocampal CA1 area participate in context fear extinction by affecting extinction-induced molecular remodeling of excitatory synapses

open access: yeseLife
The ability to extinguish contextual fear in a changing environment is crucial for animal survival. Recent data support the role of the thalamic nucleus reuniens (RE) and its projections to the dorsal hippocampal CA1 area (RE→dCA1) in this process ...
Magdalena Ziółkowska   +7 more
doaj   +1 more source

Effects of calcium on drinking fluorosis-induced hippocampal synaptic plasticity impairment in the offspring of rats

open access: yesTranslational Neuroscience, 2017
This study investigated the effects of calcium on fluorosis-induced impairment in learning and memory of offspring rats. Methods Seventy-five newly weaned female Sprague–Dawley (SD) rats were randomly divided into five groups as follows: Control group ...
Zigu Zhang   +5 more
doaj   +1 more source

Point Neurons with Conductance-Based Synapses in the Neural Engineering Framework [PDF]

open access: yesarXiv, 2017
The mathematical model underlying the Neural Engineering Framework (NEF) expresses neuronal input as a linear combination of synaptic currents. However, in biology, synapses are not perfect current sources and are thus nonlinear. Detailed synapse models are based on channel conductances instead of currents, which require independent handling of ...
arxiv  

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