Results 151 to 160 of about 352,422 (329)
THE OCCURRENCE OF A SUBUNIT PATTERN IN THE UNIT MEMBRANES OF CLUB ENDINGS IN MAUTHNER CELL SYNAPSES IN GOLDFISH BRAINS [PDF]
J. David Robertson
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Parasubthalamic Glutamatergic Neurons Coordinate Cardiovascular Homeostasis and Locomotion in Mice
PSTNVglut2 neurons function as a new central baroreflex hub via projections to the NTS, modulating parasympathetic cardiac output to maintain cardiovascular homeostasis while synchronously regulating locomotion. Blood pressure fluctuations negatively correlate with locomotor performance.
Ming‐Xuan Lu+8 more
wiley +1 more source
An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy
This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma+14 more
wiley +1 more source
Effects of mecamylamine on the Golgi recurrent collateral—Renshaw-cell synapse in the spinal cord [PDF]
S Ueki, K. Koketsu, Edward F. Domino
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We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich+8 more
wiley +1 more source
Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo+10 more
wiley +1 more source
Pharmacological investigations on a central synapse operated by acetylcholine
J. C. Eccles+2 more
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The finer structure of synapses and neurones [PDF]
P. Glees, Karl Meller
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Brain‐Inspired Polymer Dendrite Networks for Morphology‐Dependent Computing Hardware
Although process variability is often perceived as a drawback in electronics, this work harnesses the stochastic nature of electropolymerization as a powerful ally for computation. The resulting conductive polymer dendrites exhibit unique structure‐property relationships and support in memory computing, paving the way for the development of a new class
Corentin Scholaert+3 more
wiley +1 more source