Results 301 to 310 of about 187,009 (324)
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Science, 2021
Adenosine fine-tunes the fate of nascent synapses in brain ...
Blum, David, Lopes, Luísa
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Adenosine fine-tunes the fate of nascent synapses in brain ...
Blum, David, Lopes, Luísa
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Mitochondria at the Synapse [PDF]
The Neuroscientist, 2006 Synapses are packed with mitochondria, complex organelles with roles in energy metabolism, cell signaling, and calcium homeostasis. However, the precise mechanisms by which mitochondria influence neurotrans mission remain undefined. In this review, the authors discuss pharmacological and genetic analyses of synaptic mitochondrial function, focusing on
Cindy V. Ly, Patrik Verstreken
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European Journal of Neuroscience, 2014
AbstractIt has been several decades since synaptic dysfunction was first suggested to play a role in schizophrenia, but only in the last few years has convincing evidence been obtained as progress has been made in elucidating the genetic underpinnings of the disorder.
Michael Conlon O'Donovan +2 more
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AbstractIt has been several decades since synaptic dysfunction was first suggested to play a role in schizophrenia, but only in the last few years has convincing evidence been obtained as progress has been made in elucidating the genetic underpinnings of the disorder.
Michael Conlon O'Donovan +2 more
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Nature Reviews Neuroscience, 2002
Post-translational modification by the attachment of ubiquitin seems to have a crucial role in regulating synaptic structure and function. By controlling the stability, activity and localization of target proteins, this versatile regulatory system can shape the pattern, activity and plasticity of synaptic connections.
Ashok N. Hegde, Aaron DiAntonio
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Post-translational modification by the attachment of ubiquitin seems to have a crucial role in regulating synaptic structure and function. By controlling the stability, activity and localization of target proteins, this versatile regulatory system can shape the pattern, activity and plasticity of synaptic connections.
Ashok N. Hegde, Aaron DiAntonio
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Nature Methods, 2014 A combination of experimental protein analysis and imaging techniques is used to create a three-dimensional model of a synaptic bouton.
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Molecular Immunology, 2002
The immunological synapse plays a central role in organising the immune system. Through their synaptic activity both T and B cells usually, but not always, acquire the information that critically determines the level and nature of the responses that they make. For T cells much of that information comes from epicrine and paracrine cell-cell interactions
N.M. Terazzini +2 more
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The immunological synapse plays a central role in organising the immune system. Through their synaptic activity both T and B cells usually, but not always, acquire the information that critically determines the level and nature of the responses that they make. For T cells much of that information comes from epicrine and paracrine cell-cell interactions
N.M. Terazzini +2 more
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Proteolytic activity, synapse elimination, and the Hebb synapse
Journal of Neurobiology, 1994AbstractThe Hebb synapse has been postulated to serve as a mechanism subserving both regulation of synaptic strength in the adult nervous system (long‐term potentiation and depression) and developmental activity‐dependent plasticity. According to this model, pre‐ and postsynaptic temporal concordance of activity results in strengthening of connections,
Fields Rd +4 more
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Synapse selection based on differences in synapse turnover
International Journal of Developmental Neuroscience, 1983AbstractRat retinal neurons formed transient synapses with rat muscle cells in culture only during a discrete period in development, from the 20th day of embryonic development to the 7th neonatal day. In contrast, chick embryo spinal cord neurons formed synapses at all developmental stages tested, from the 2nd to the 18th day of embryonic development ...
Jeffrey M. Thompson +3 more
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Journal of Molecular Biology, 1996
We describe a simple innovation that allows DNA double helices to stably bind one another at specific sites, with regulatable affinity, under physiological conditions. This type of DNA synapsis requires neither an unraveling of the participating duplexes not heteroduplex formation, and is achieved by the intermolecular dimerization of short blocks of ...
E A, Venczel, D, Sen
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We describe a simple innovation that allows DNA double helices to stably bind one another at specific sites, with regulatable affinity, under physiological conditions. This type of DNA synapsis requires neither an unraveling of the participating duplexes not heteroduplex formation, and is achieved by the intermolecular dimerization of short blocks of ...
E A, Venczel, D, Sen
openaire +2 more sources