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Single-molecule techniques in studying the molecular mechanisms of DNA synapsis in non-homologous end-joining repair. [PDF]

Biophys Rep
Jiang Y, Zhao C, Zhang C, Li W, Liu D, Zhao B.   +5 more
europepmc   +1 more source

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Chromosome synapsis in hexaploids

Journal of Theoretical Biology, 1980
Abstract Theoretical relationships between pachytene multivalent and bivalent frequencies in hexaploids are deduced from a model, based on chromosomes showing sequential association at equidistant pairing sites and uniform propensities for partner exchange throughout their lengths.
R S, Callow, I, Gladwell
openaire   +2 more sources

On transmission of information by synapsis

International Journal of Bio-Medical Computing, 1970
Abstract This study is a solution to a problem of information transmission by synapsis which is reduced to the integration of the equation with partial derivatives of the heat type with mixed conditions. The solution z(x, t) found is represented by an integral of Fourier series which tends to a singular integral in the neighbourhood of x = 0+, the
Badescu, R., Balaceanu, C., Nicolau, E.
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Chromosome rotation and formation of synapsis

Nature, 1976
ALTHOUGH the rotation and oscillation of the nuclei of cultured spermatocytes have been known for some years1,2, no correlations of this phenomenon with the stages of mitosis or meiosis, or with the biochemical or cytogenetic events during germ-cell development have been made.
M, Parvinen, K O, Söderström
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Synapsis or silence

Nature Genetics, 2005
The XY chromosome pair in mammalian males is sequestered into a transcriptionally dormant chromatin domain before the first meiotic division. New work shows that all chromosomes can suffer the same fate if they don't pair during meiosis, and that this may be part of a surveillance mechanism to protect against aneuploid gametes.
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Synapsis and recombination in inversion heterozygotes

Biochemical Society Transactions, 2010
Inversion heterozygotes are expected to suffer from reduced fertility and a high incidence of chromosomally unbalanced gametes due to recombination within the inverted region. Non-homologous synapsis of the inverted regions can prevent recombination there and diminish the deleterious effects of inversion heterozygosity.
Anna A, Torgasheva, Pavel M, Borodin
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Checkpoint for Synapsis

Science, 2005
The complex mechanics of the eukaryotic cell cycle is monitored at a number of points to ensure that everything is going according to plan before the next step in the process is executed. Known checkpoints include DNA replication, DNA damage, and spindle function. Bhalla and Dernburg identify a checkpoint that monitors synapsis, or pairing
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Synapsis in a natural autotetraploid

Genome, 1999
To test assumptions of the autotetraploid chromosome pairing model regarding events during synapsis, whole-mount spreads of synaptonemal complexes (SCs) of Machaeranthera pinnatifida (=Haplopappus spinulosus) (Asteraceae) (2n = 4x = 16) were analyzed by electron microscopy. On the assumption of one synaptic initiation per chromosome arm, each pachytene
Donald P. Hauber, Aaron Reeves, Stephen M. Stack   +2 more
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On the mechanism of homologous synapsis in lycosid spiders

Genome, 1995
Lycosid spiders have 13 pairs of telocentric chromosomes and 2 nonhomologous sex chromosomes in males. At leptotene, the kinetochore ends are attached to the nuclear envelope via thickened attachment plaques. Homologous synapsis begins at the attachment plaques and proceeds zipper-like through the length of the synaptonemal complex.
D A, Wise, J L, Taylor
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