Results 211 to 220 of about 14,796 (289)

Germline-Restricted Chromosome (GRC) in Diploid and Polyploid Spermatocytes of the Eurasian Bullfinch, <i>Pyrrhula pyrrhula</i> (Fringillidae, Passeriformes, Aves). [PDF]

Animals (Basel)
Grishko E, Malinovskaya L, Tishakova K, Borodin P.   +3 more
europepmc   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

Advanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu, Zitian Zheng, Feiran Wang, Huanhuan Luo, Fei Ju, Yucheng Zhu, Zheng Zhou, Jie Sun, Zhenghui Qiu, Xiang Luo, Zhongzheng Jia, Jianquan Wang, Hongjie Huang, Bo Zhang   +13 more
wiley   +1 more source

Two structurally mobile regions control the conformation and function of metamorphic meiotic HORMAD proteins. [PDF]

Nat Commun
Barroso C, Prince JP, Rattu P, Sacerdoti M, Koundé D, Ferrandiz N, Lopez-Jimenez P, Khalid S, Martinez-Perez E.   +8 more
europepmc   +1 more source

A Bio‐Inspired Visual Sensor With UV‐to‐NIR Fusion for Enhanced Recognition in Autonomous Driving Systems

Advanced Science, EarlyView.
Inspired by the sophisticated multilayer retinal architecture found in Pacific salmon eyes, a novel van der Waals heterojunction sensor based on NbNiTe5/BP is designed. Upon illumination at distinct wavelengths of 365 and 820 nm, the device exhibits distinctive bipolar photocurrent responses with opposite polarities. This unique optoelectronic behavior
Tianle Zeng, Zishen Zhao, Keqin Tang, Yawen Luo, Junxin Yan, Kun Ye, Jinlu Liu, Zhuo Dong, Zhipeng Yu, Weiming Lv, Ruicheng Li, Yenasheng Li, Lixuan Liu, Tianyu Xue, Chun Zhao, Yan Zhou, Kai Zhang, Zhongming Zeng, Zhongyuan Liu   +18 more
wiley   +1 more source

Critical roles of MCM8 in meiotic recombination during mouse spermatogenesis

Surarapu LK, Tilton K, Stritto MRD, Acharya A, Menendez AM, Lu M, Shaheen N, Liang S, Iyer M, Cejka P, Pratto F, Jain D.   +11 more
europepmc   +1 more source

Meiotic pairing through barcode-like satellite DNA repeats. [PDF]

Nat Commun
Skrutl L, Chavan A, Sintsova A, Ceppi I, Ropp CJ, Sunagawa S, Cejka P, Jagannathan M.   +7 more
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis. [PDF]

Cell Prolif
Liu K, Zhang W, Jiang X, Chen J, Zhu L, Zhang Z, Gu J, Guo L, Ao L, Chen Q, Sun L, Hu Y, Wang X, Liu Y, Cao J, Han F, Liu J.   +16 more
europepmc   +1 more source

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee, Gayeon Kim, Ellison R. Black, Seonil Kim   +3 more
wiley   +1 more source

Ubc9 Mediates SUMO2/3 Modification to Regulate Meiosis in Male Mice. [PDF]

Biomedicines
Lv P, Xu W, Yang B, Xu D, Wang T, Liu J, Liu X.   +6 more
europepmc   +1 more source