Results 41 to 50 of about 1,268 (267)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Phonological Variation Technology Integration for Indonesia Cultural Preservation and Edupreneurship

Aptisi Transactions on Technopreneurship
This study explores phonological variations in the Komering dialects of South Sumatra, Indonesia, examining differences in vowel and consonant phonemes influenced by geographical and socio-cultural factors.
Hetilaniar Hetilaniar, Ida Zulaeha, Hari Bakti Mardikantoro, Tommi Yuniawan, Nicholas Lachlan   +4 more
doaj   +1 more source

The productivity of ‘unnatural’ labial palatalization in Xhosa

Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2016
Xhosa (Bantu, South Africa) has a pattern of labial palatalization.  When the passive suffix /-w-/ is added to a stem ending in a labial, the labial becomes palatal (uku-lum-a → uku-luɲ-w-a).
Wm. G. Bennett, Aaron Braver
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Variación dialectal y evolución lingüística : los idiomas romances de la Península Ibérica

Études romanes de Brno, 2013
In this paper we try to illustrate with modern and medieval iberoromanic examples the connection between dialectal variation and history of languages. We defend that actual dialectal variation may reflect old structures.
Tibor Berta
doaj  

On the nature of the phonetic-phonologic change: the cases of /nj/ and /lj/

Revista de Filología Románica, 2016
Phonetic change has been described for almost a century though from an articulatory perspective and only taking into account written documents. Recently, new theories have claimed that diachronic change could be explained throughout synchronic variation ...
Assumpció Rost Bagudanch
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Diachronic and/or synchronic variation? [PDF]

, 2007
A majority of the early research in Second Language Acquisition focused on diachronic variation in the learners’ interlanguage (IL), that is, differences in the IL linked to a supposed increase in knowledge between two points in time (cf. Tarone 1988). The last decade has seen an increase in studies combining a diachronic perspective with a synchronic ...
openaire   +1 more source