BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Characterizing perfect recall using next-step temporal operators in S5 and sub-S5 Epistemic Temporal Logic [PDF]
We review the notion of perfect recall in the literature on interpreted systems, game theory, and epistemic logic. In the context of Epistemic Temporal Logic (ETL), we give a (to our knowledge) novel frame condition for perfect recall, which is local and
Witzel, Andreas
core
A process algebra for synchronous concurrent constraint programming [PDF]
Concurrent constraint programming is classically based on asynchronous communication via a shared store. This paper presents new version of the ask and tell primitives which features synchronicity.
Brim, L +3 more
core +4 more sources
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Cognitive Modulation of Local and Callosal Neural Interactions in Decision Making
Traditionally, the neurophysiological mechanisms of cognitive processing have been investigated at the single cell level. Here we show that the dynamic, millisecond-by-millisecond, interactions between neuronal events measured by local field potentials ...
Hugo eMerchant +3 more
doaj +1 more source
Self-synchronization and controlled synchronization
An attempt is made to give a general formalism for synchronization in dynamical systems encompassing most of the known definitions and applications. The proposed set-up describes synchronization of interconnected systems with respect to a set of functionals and captures peculiarities of both self-synchronization and controlled synchronization.
Nijmeijer, H. +3 more
openaire +2 more sources
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Imaginaire linguistique et dynamique langagière. Aspects théoriques et méthodologiques
Research on the Linguistic Imaginary or "the speaker's relationship to Language and its actualisations (uses)" starts from the following theoretical and methodological points of view: linguistic study is dynamic synchronic. It is not only descriptive but
Anne-Marie Houdebine-Gravaud
doaj +1 more source
Synchronous vs. asynchronous dynamics of diffusion-controlled reactions [PDF]
An analytical method based on the classical ruin problem is developed to compute the mean reaction time between two walkers undergoing a generalized random walk on a 1d lattice.
Albano +30 more
core +1 more source
Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen +18 more
wiley +1 more source

