Results 61 to 70 of about 11,093 (266)

Temps de la chose-racontée et temps du récit vidéoludique : comment le jeu vidéo raconte ?

open access: yesSciences du Jeu, 2018
Starting with a reflection on the application in game studies of Christian Metz’s consideration of the narrative as a double temporal sequence between the time of the thing told and the time of the narrative (2013, p.
Rémi Cayatte
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Synchronicity: An Unfinished Journey

open access: yesMediterranean Journal of Clinical Psychology
Jung and Pauli found a link between the psyche and quantum mechanics by formulating the idea of Synchronicity. Synchronicity provides a conceptual acausal framework for both meaningful coincidences of life and random physical events of the quantum world.
Alessandro Sergi   +3 more
doaj   +1 more source

Articulation and Dynamics Influence the Perceptual Attack Time of Saxophone Sounds

open access: yesFrontiers in Psychology, 2018
Perceptual attack time (PAT) is defined as the moment when the most salient rhythmical feature of a sound is perceived. This paper focuses on the PAT of saxophone sounds, investigating how the location of this point in time changes when a note is played ...
Toni Amadeus Bechtold, Olivier Senn
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Brennand: resonancia y universalidad de las formas Brennand: resonance and the univesality of the forms

open access: yesRevista Chilena de Historia Natural, 2001
Este trabajo propone la búsqueda y exposición de patrones de formas, tanto de algunas obras producidas por la naturaleza como de algunas de las obras producidas por la mano del hombre, quien como un microcosmos, que forma parte de la naturaleza recrea el
G. CECILIA TORO
doaj  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

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