Results 91 to 100 of about 329,788 (319)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Indian Journal of Medical and Paediatric Oncology, 2019 Background: Encountering more than one malignancy in a cancer patient is no longer uncommon; this increasing incidence is mostly attributable to the improvements in life expectancy, awareness, and diagnostic facilities.
Niharika Bisht +10 more
doaj +1 more source
, 2003 The reverse-link performance of synchronous DS-CDMA is investigated in Rician multipath fading environments. The numerical results show that the performance benefits of synchronous transmission depend on the specular path’s power as well as on the ...
Hwang, S.H., Hanzo, L.
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A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Associations of Sleep and Shift Work With Osteoarthritis Risk
Arthritis Care &Research, EarlyView.Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge +6 more
wiley +1 more source
Student Perceptions of Effective Educators in Online Learning
Online LearningThis research project surveyed college students about their experiences with online learning in the aftermath of the move to Emergency Remote Teaching (ERT). Specifically, students reported on strategies they appreciate in an online instructor.
Erica Kelly +2 more
doaj +1 more source
Tree parsing with synchronous tree-adjoining grammars
, 2011 Restricting the input or the output of a grammar-induced translation to a given set of trees plays an important role in statistical machine translation. The problem for practical systems is to find a compact (and in particular, finite) representation of ...
Vogler, Heiko +2 more
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, 2001 Kretzberg J, Egelhaaf M, Warzecha A-K. Membrane potential fluctuations determine the precision of spike timing and synchronous activity: a model study. Journal of computational neuroscience.
Egelhaaf, Martin ; https://orcid.org/ +2 more
core +1 more source