Results 51 to 60 of about 330,381 (303)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Synchronous Motors (Part 1 of 2)

open access: yes, 2023
This video, published by Columbia Gorge Community College, is the first part of a two part lecture on electrically excited synchronous motors. The lecture covers synchronous motor construction and theory of operation along with the electrical and ...
Pytel, Jim
core   +1 more source

Control of Permanent Magnet Synchronous Motors for Track Applications

open access: yes, 2023
For a wide variety of motion control systems, the PMSM (Permanent Magnet Synchronous Motors) drive is among the best options. The PMSMs, for instance, are frequently used for motors, power tools, and robotics and are currently being explored for high ...
Paolo Mercorelli
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Current Control of Electrolytic Capacitor-Less Variable Frequency Drive System for Synchronous Reluctance Motors Based on Power Balancing and Compensation

open access: yesIEEE Access
The electrolytic capacitor-less variable frequency drive scheme using film capacitors to replace electrolytic capacitors has been partially applied in the field of washing machines and air conditioners driven by permanent magnet synchronous motors, due ...
Weican Yan   +5 more
doaj   +1 more source

ROTOR STRUCTURE WITH DOUBLE CAGE FOR IMPROVED SYNCHRONOUS CAPABILITY OF LINE-START PERMANENT MAGNET SYNCHRONOUS MOTORS

open access: yesТехнічна електродинаміка, 2020
Line start permanent magnet synchronous motors (LSPMSMs) have a problem of synchronization. In this paper the rotor of LSPMSM with double cage is proposed to improve synchronous capability of the motor. Key factors concerning the starting performance and
Hongbo Qiu   +3 more
doaj   +1 more source

Hybrid Excitation PM Synchronous Motors: Part II - Finite Element Analysis

open access: yes, 2021
This paper deals with the finite element analysis of Hybrid Excitation Permanent Magnet Synchronous Motors, that is, synchronous motors characterised by a rotor including both permanent magnets and an excitation winding.
Cinti L.   +5 more
core   +1 more source

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