Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su+12 more
wiley +1 more source
A miniature X-ray diffraction setup on ID20 at the European Synchrotron Radiation Facility. [PDF]
Sahle CJ+9 more
europepmc +1 more source
Protein microcrystal diffraction and the effects of radiation damage with ultra-high-flux synchrotron radiation. [PDF]
Britt Hedman+4 more
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Transition metal (TM) slab gliding is a key process for activating anionic redox reaction in P‐type layered oxide materials. Disordered TM layer weakens interlayer interactions and facilitates TM slab gliding. The resulting O‐type layer promotes reversible TM migration, provides the necessary Na–O–□TM configuration, and activates anionic redox reaction.
Dongxiao Wang+12 more
wiley +1 more source
30 years of Journal of Synchrotron Radiation and synchrotron science. [PDF]
Hasnain SS.
europepmc +1 more source
Effects of synchrotron radiation on the compression of a relativistic electron layer
D. Nowak
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Examination of thermally induced deformation of a synchrotron radiation mirror using finite element analysis [PDF]
Cristina Lenardi+3 more
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The manuscript designs a type of SA Mn‐CDs with low coordination Mn‐N2 configuration hydrothermally synthesized by chelating manganese atoms with ethylenediamine tetraacetic acid. SA Mn‐CDs not only have more active sites at the atomic level for high efficiently peroxidase‐like activity but also show excellent fluorescent ability at the cellular and ...
Peiwei Jin+8 more
wiley +1 more source
Crystal growth and characterization of 1-inch GTAGG: Ce single crystal for sub-micron resolution synchrotron radiation X-ray imaging. [PDF]
Omuro K+17 more
europepmc +1 more source
Time domain double slit interference of electron produced by XUV synchrotron radiation. [PDF]
Kaneyasu T+6 more
europepmc +1 more source