Results 191 to 200 of about 94,006 (299)

EBHIS Local Volume Galaxy Hi Survey (LVGHIS)

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT Here, we present the “Local Volume Galaxy Hi Survey” (LVGHIS). It is based on the first data release of the Milky Way portion of the Effelsberg Bonn Hi‐Survey (EBHIS). We homogeneously measured the mass and dynamics of the local volume galaxies within the radial velocity limit of |vLSR|≤600kms−1$$ \mid {v}_{\mathrm{LSR}}\mid \le 600\kern0.6em \
V. A. Schulz   +3 more
wiley   +1 more source

Case Study of a Fly's Eye Homogenizer for the Calibration Illumination of Integral Field Units

open access: yesAstronomische Nachrichten, EarlyView.
ABSTRACT Integral‐field unit spectrographs require a homogeneous calibration illumination of the field of view for proper flat and wavelength calibration (e.g., BlueMUSE which is currently under development for the VLT). This article presents the adaptation of a fly's eye homogenizer, frequently used in laser applications, to this task in astronomical ...
Daniel P. Sablowski   +4 more
wiley   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort   +8 more
wiley   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

Particular Aspects of Cardiac Rhythm Disorders in Symptomatic Children and Adolescents. [PDF]

open access: yesChildren (Basel)
Constantin GB   +5 more
europepmc   +1 more source

Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: A model‐based simulation of the positioning imatinib for pulmonary arterial hypertension trial

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
ABSTRACT Aims Imatinib improves hemodynamics in pulmonary arterial hypertension (PAH), but dose‐dependent toxicity has limited its clinical development. We aimed to quantify the dose–efficacy–toxicity relationship and evaluate alternative dosing strategies using data from the PIPAH trial.
Medhat M. Said   +13 more
wiley   +1 more source

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