Results 41 to 50 of about 129,816 (327)

The investigation of syncope [PDF]

open access: yesSeizure, 2004
Patients with syncope are usually referred to either neurology or cardiology clinics, yet the facilities for detailed syncope investigation are mostly in cardiac units. The diagnosis rests principally upon the history, but investigations may be required to support the clinical diagnosis.
Savvas Hadjikoutis   +2 more
openaire   +3 more sources

Correlation between percutaneous patent foramen ovale closure and recurrence of unexplained syncope

open access: yesFrontiers in Neurology, 2023
BackgroundThe relationship between patent foramen ovale (PFO) and unexplained syncope remains to be illustrated. Therefore, this study aimed to explore the outcomes and prognostic factors for syncope recurrence after PFO closure.MethodsPatients with both
Xianwen Wang   +6 more
doaj   +1 more source

Episodic neurologic disorders: syndromes, genes, and mechanisms. [PDF]

open access: yes, 2013
Many neurologic diseases cause discrete episodic impairment in contrast with progressive deterioration. The symptoms of these episodic disorders exhibit striking variety.
Fu, Ying-Hui   +2 more
core   +2 more sources

Listening to syncope [PDF]

open access: yesInternational Journal of Emergency Medicine, 2009
A 35-year-old man presented with progressive exertional dyspnea (3 months) and syncopal attacks (1 week). He had tachypnea, tachycardia and hypotension. Examination revealed a mid-diastolic plop at the apex. Clinical suspicion was a left atrial mass with a ball valve-like mechanism (LA thrombus or LA tumors).
Guruprasad Sogunuru, Kishan Vuddanda
openaire   +3 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Diagnostic and societal impact of implementing the syncope guidelines of the European Society of Cardiology (SYNERGY study)

open access: yesBMC Medicine, 2023
Background Syncope management is fraught with unnecessary tests and frequent failure to establish a diagnosis. We evaluated the potential of implementing the 2018 European Society of Cardiology (ESC) Syncope Guidelines regarding diagnostic yield ...
M. Ghariq   +17 more
doaj   +1 more source

Brugada Syndrome: Presentation and Management of the Atypical Patient in the Emergent Setting [PDF]

open access: yes, 2020
Introduction: Brugada syndrome is a genetic disorder of the heart’s electrical system that increases a patient’s risk of sudden cardiac death. It is a syndrome most prevalent in Southeast Asians and is found 36 times more commonly in Asians than in ...
Flores, Mario   +2 more
core  

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. [PDF]

open access: yes, 2013
BACKGROUND: Riociguat, a member of a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension. METHODS: In this phase 3,
CHEST-1 Study Group,   +13 more
core   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Case report: Recurrent syncope as initial symptom in a patient with neck lymphoma

open access: yesFrontiers in Cardiovascular Medicine, 2022
Syncope may have many different causes, requiring careful identification. Recurrent syncope is uncommon as an initial symptom of neck lymphoma. Head and neck tumors involving the carotid artery cause syncope associate with carotid sinus syndrome.
Yanfang Wu   +9 more
doaj   +1 more source

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