Results 11 to 20 of about 9,762 (167)

Syndactyly genes and classification: a mini review

Journal of Biochemical and Clinical Genetics, 2018
Syndactyly (Syn = together; Dactylos = digits) is the most common limb defect mostly characterized by webbing of digits. It may be webbing with or without bony fusion and inherited mostly in autosomal dominant manner, although also reported as autosomal ...
Muhammad Umair, Farooq Ahmad, Muhammad Bilal, Safdar Abbas   +3 more
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Two nonsense GLI3 variants are associated with polydactyly and syndactyly in two families by affecting the sonic hedgehog signaling pathway

Molecular Genetics & Genomic Medicine, 2022
Background Polydactyly and syndactyly are congenital limb deformities, segregating in an autosomal‐dominant fashion. The variants in the GLI3 gene are closely related to congenital limb malformations.
Xiaofang Shen, Shun Zhang, Xin Zhang, Taifeng Zhou, Yongjun Rui   +4 more
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A Complex Case of Clino-Syndactyly with Fourth Metacarpal Aplasia

Life, 2023
Syndactyly is the most common congenital malformation of the hand, leading to the fusion of the digits and frequently affecting the ring and middle fingers.
Hermann Nudelman, Aba Lőrincz, Anna Gabriella Lamberti, Tamás Kassai, Gergő Józsa   +4 more
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Integration, heterochrony, and adaptation in pedal digits of syndactylous marsupials

BMC Evolutionary Biology, 2008
Background Marsupial syndactyly is a curious morphology of the foot found in all species of diprotodontian and peramelemorph marsupials. It is traditionally defined as a condition in which digits II and III of the foot are bound by skin and are reduced ...
Nilsson Maria, Weisbecker Vera
doaj   +1 more source

Genetic determinants of syndactyly: perspectives on pathogenesis and diagnosis

Orphanet Journal of Rare Diseases, 2022
The formation of the digits is a tightly regulated process. During embryogenesis, disturbance of genetic pathways in limb development could result in syndactyly; a common congenital malformation consisting of webbing in adjacent digits.
Afraah Cassim, Dineshani Hettiarachchi, Vajira H. W. Dissanayake   +2 more
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Comparative study between Hexagonal and Rectangular Flaps for Web Reconstruction of Simple Syndactyly of the Fingers [PDF]

Al-Azhar International Medical Journal
Background: Syndactyly is a common congenital hand anomaly, affecting one in every 2000 live births, and can be classified as complex, simple, complicated, or syndromic.
Gaber Osman, Mohamed Ouf, Mahmoud El-Hendawy, Mahmoud Ali   +3 more
doaj   +2 more sources

Predictive Factors of Keloid Formation in Congenital Foot Syndactyly

Plastic and Reconstructive Surgery, Global Open, 2021
Background:. Keloid formation after syndactyly division is a stressful situation for patients. In our experience, digital enlargement may be involved in keloid formation following syndactyly divisions.
Sang Ho Oh, MD, Sang Hyun Woo, MD, PhD
doaj   +1 more source

Genetic Overview of Syndactyly and Polydactyly

Plastic and Reconstructive Surgery, Global Open, 2017
Summary:. Syndactyly and polydactyly—respectively characterized by fused and supernumerary digits—are among the most common congenital limb malformations, with syndactyly presenting at an estimated incidence of 1 in 2,000–3,000 live births and ...
Humayun Ahmed, BA, Hossein Akbari, MD, Abdolhasan Emami, MD, Mohammad R. Akbari, MD, PhD   +3 more
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Keeping you on your toes: Smith–Lemli–Opitz Syndrome is an easily missed cause of developmental delays

Clinical Case Reports, 2023
Smith‐Lemli‐Opitz syndrome (SLOS) is a relatively common genetic cause of developmental delay and may only present in conjunction with 2,3 toe syndactyly.
Simone Coupe, Ashley Hertzog, Carolyn Foran, Adviye Ayper Tolun, Megan Suthern, Clara W. T. Chung, Carolyn Ellaway   +6 more
doaj   +1 more source

Sub-Exome Target Sequencing in a Family With Syndactyly Type IV Due to a Novel Partial Duplication of the LMBR1 Gene: First Case Report in Fujian Province of China

Frontiers in Genetics, 2020
Syndactyly is one of the most frequent hereditary limb malformations with clinical and genetical complexity. Autosomal dominant syndactyly type IV (SD4) is a rare form of syndactyly, caused by heterozygous mutations in a sonic hedgehog (SHH) regulatory ...
Lijing Shi, Hui Huang, Qiuxia Jiang, Rongsen Huang, Wanyu Fu, Liangwei Mao, Liangwei Mao, Xiaoming Wei, Huanhuan Cui, Keke Lin, Licheng Cai, You Yang, Yuanbai Wang, Jing Wu   +13 more
doaj   +1 more source