Results 121 to 130 of about 5,596,228 (313)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Syndromic approach in assessing the surgical pathology of the cervical spine
Гений oртопедии, 2018 Object of study The existing variety of cervical spine pathologies resulted in a huge number of nosologic classifications and complicates their interpretation.
Alexander V. Burtsev +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A Child with Aarskog Scott Syndrome and Autism Spectrum Disorder
Sakarya Tıp DergisiAutism Spectrum Disorder (ASD) is a neurodevelopmental disorder that is increasingly common in society, characterized by limitations in social communication and some repetitive behaviors.
Nur Seda Gülcü Üstün
doaj +1 more source
Case report : Williams-Campbell syndrome [PDF]
, 2009 Background: Williams-Campbell syndrome is a rare type of bronchiectasis that is due to deficiency or absence of cartilage in the fourth- to sixth-order bronchi.
Bestry, Iwona +3 more
core
Oculocerebral hypopigmentation syndrome (Cross syndrome).
The Turkish journal of pediatrics, 1991 A typical case of Cross syndrome with hypopigmentation, mental and psychomotor retardation, spasticity, bilateral optic atrophy and dental defects in a three-year-old boy is presented. The clinical features of this rare syndrome are discussed.
ÖZKAN, HASAN, UNSAL, E, KOSE, G
openaire +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
GAPO Syndrome – Diagnosis of a Rare Case Report and Review
Journal of Indian Academy of Oral Medicine and RadiologyGAPO syndrome is an unusual genetic disorder with an autosomal recessive trait inheritance. The syndrome is caused due a genetic defect or alterations in the ANTXR1/TEM8 gene.
Sindhu Vijayakumar +1 more
doaj +1 more source
Gastric pseudoaneurysm in the setting of Loey’s Dietz Syndrome [PDF]
, 2012 Loey’s Dietz syndrome is a disorder of connective tissue caused by a mutation in the genes that encode transforming growth factor (TGF) beta receptor 1 and 2.
Johston, Troy Alan, Likes, Maggie L.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source