Results 61 to 70 of about 618,618 (261)

Evaluation of outbreak detection performance using multi-stream syndromic surveillance for influenza-like illness in rural Hubei Province, China: a temporal simulation model based on healthcare-seeking behaviors.

PLoS ONE, 2014
BackgroundSyndromic surveillance promotes the early detection of diseases outbreaks. Although syndromic surveillance has increased in developing countries, performance on outbreak detection, particularly in cases of multi-stream surveillance, has ...
Yunzhou Fan, Ying Wang, Hongbo Jiang, Wenwen Yang, Miao Yu, Weirong Yan, Vinod K Diwan, Biao Xu, Hengjin Dong, Lars Palm, Shaofa Nie   +10 more
doaj   +1 more source

Beyond traditional surveillance: applying syndromic surveillance to developing settings – opportunities and challenges

BMC Public Health, 2009
Background All countries need effective disease surveillance systems for early detection of outbreaks. The revised International Health Regulations [IHR], which entered into force for all 194 World Health Organization member states in 2007, have expanded
Chretien Jean-Paul, May Larissa, Pavlin Julie A   +2 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Outbreak detection and evaluation of a school-based influenza-like-illness syndromic surveillance in Tianjin, China.

PLoS ONE, 2017
School-based influenza-like-illness (ILI) syndromic surveillance can be an important part of influenza community surveillance by providing early warnings for outbreaks and leading to a fast response.
Wenti Xu, Tianmu Chen, Xiaochun Dong, Mei Kong, Xiuzhi Lv, Lin Li   +5 more
doaj   +1 more source

Evaluation of the ability of standardized supports to improve public health response to syndromic surveillance for respiratory diseases in Canada

BMC Public Health, 2017
Background Despite widespread implementation of syndromic surveillance systems within public health agencies, previous studies of the implementation and use of these systems have indicated that the functions and responses taken in response to syndromic ...
Laura A. Rivera, Ye Li, Rachel D. Savage, Natasha S. Crowcroft, Shelly Bolotin, Laura C. Rosella, Wendy Lou, Jessica Hopkins, Ian Gemmill, Ian Johnson   +9 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Medication Sales and Syndromic Surveillance, France

Emerging Infectious Diseases, 2006
Although syndromic surveillance systems using nonclinical data have been implemented in the United States, the approach has yet to be tested in France. We present the results of the first model based on drug sales that detects the onset of influenza season and forecasts its trend.
Vergu, Elisabeta, F. Grais, Rebecca, Sarter, Hélène, Fagot, Jean-Paul, Lambert, Bruno, Valleron, Alain-Jacques, Flahault, Antoine   +6 more
openaire   +7 more sources

Meta-Analysis of the Accuracy of Syndromic Surveillance

CoRR, 2022
We present the first meta-analysis of co-evolutionary learning networks for digital disease surveillance research over last 10 years. In doing so, we show the co-evolution and dynamical changes that occurred in academic research related to digital disease surveillance for improving accuracy, approach and results.
Liaquat Hossain, Derek Kham
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source