Results 31 to 40 of about 5,212 (112)

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Exploring native genetic elements as plug-in tools for synthetic biology in the cyanobacterium Synechocystis sp. PCC 6803

Microbial Cell Factories, 2018
Background The unicellular cyanobacterium Synechocystis sp. PCC 6803 has been widely used as a photoautotrophic host for synthetic biology studies. However, as a green chassis to capture CO2 for biotechnological applications, the genetic toolbox for ...
Deng Liu, Himadri B. Pakrasi
doaj   +1 more source

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

The FEBS Journal, EarlyView.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat, Margot Beltran, Juliette Schnoebelen, Laura Flandrin, Wafa Rezali, Eline Michel, Sophie S. Abby, Fabien Pierrel   +7 more
wiley   +1 more source

Diurnal Regulation of Cellular Processes in the Cyanobacterium Synechocystis sp. Strain PCC 6803: Insights from Transcriptomic, Fluxomic, and Physiological Analyses

mBio, 2016
Synechocystis sp. strain PCC 6803 is the most widely studied model cyanobacterium, with a well-developed omics level knowledgebase. Like the lifestyles of other cyanobacteria, that of Synechocystis PCC 6803 is tuned to diurnal changes in light intensity.
Rajib Saha, Deng Liu, Allison Hoynes-O’Connor, Michelle Liberton, Jingjie Yu, Maitrayee Bhattacharyya-Pakrasi, Andrea Balassy, Fuzhong Zhang, Tae Seok Moon, Costas D. Maranas, Himadri B. Pakrasi   +10 more
doaj   +1 more source

Phycocyanobilin biosynthesis in Galdieria sulphuraria requires isomerization of phycoerythrobilin synthesized by bilin reductases

The FEBS Journal, EarlyView.
The biosynthesis of bilins, tetrapyrroles essential for light harvesting and sensing, is performed by specific enzymes (FDBRs). In Galdieria sulphuraria, both phycobiliprotein types bind phycocyanobilin, despite lacking the canonical synthesizing gene PCYA. Instead, PEBA and PEBB are encoded, producing phycoerythrobilin, proposed to be later isomerized
Federica Frascogna, Nathan C. Rockwell, Jana Hartmann, Julie M. Mudler, Nicole Frankenberg‐Dinkel   +4 more
wiley   +1 more source

Effects of Inorganic Carbon Limitation on the Metabolome of the Synechocystis sp. PCC 6803 Mutant Defective in glnB Encoding the Central Regulator PII of Cyanobacterial C/N Acclimation

Metabolites, 2014
Cyanobacteria are the only prokaryotes performing oxygenic photosynthesis. Non-diazotrophic strains such as the model Synechocystis sp. PCC 6803 depend on a balanced uptake and assimilation of inorganic carbon and nitrogen sources. The internal C/N ratio
Doreen Schwarz, Isabel Orf, Joachim Kopka, Martin Hagemann   +3 more
doaj   +1 more source

Evolutionary Changes in DnaA-Dependent Chromosomal Replication in Cyanobacteria

Frontiers in Microbiology, 2020
Replication of the circular bacterial chromosome is initiated at a unique origin (oriC) in a DnaA-dependent manner in which replication proceeds bidirectionally from oriC to ter. The nucleotide compositions of most bacteria differ between the leading and
Ryudo Ohbayashi, Shunsuke Hirooka, Ryo Onuma, Yu Kanesaki, Yuu Hirose, Yusuke Kobayashi, Takayuki Fujiwara, Takayuki Fujiwara, Chikara Furusawa, Chikara Furusawa, Shin-ya Miyagishima, Shin-ya Miyagishima   +11 more
doaj   +1 more source

Cyanobacteria as multifunctional bioinputs for sustainable intensification, soil health enhancement, and climate resilience in rice‐based cropping systems

Agrosystems, Geosciences &Environment, Volume 9, Issue 1, March 2026.
Abstract Ensuring food security goals through the provision of sustainable energy and food without compromising environmental sustainability is the current requirement amid threats from climate change, uncontrolled global population, and scarcity of natural resources.
Muhammad Shahbaz Farooq, Faiza Javed, Muhammad Uzair, Hossam S. El‐Beltagi, Usman Zulfiqar, Muhammad Ramzan Khan, Muhammad Yousuf, Muximilian Tuckner, Nazih Y. Rebouh, Mohd Asif Shah   +9 more
wiley   +1 more source

Determination of Mn Concentrations in Synechocystis sp. PCC6803 Using ICP-MS

Bio-Protocol, 2017
Manganese (Mn) is an essential micronutrient for all photoautotrophic organisms. Two distinct pools of Mn have been identified in the cyanobacterium Synechocystis sp.
Fabian Brandenburg, Hanan Schoffman, Nir Keren, Marion Eisenhut   +3 more
doaj   +1 more source

A systematic overexpression approach reveals native targets to increase squalene production in Synechocystis sp. PCC 6803

Frontiers in Plant Science, 2023
Cyanobacteria are a promising platform for the production of the triterpene squalene (C30), a precursor for all plant and animal sterols, and a highly attractive intermediate towards triterpenoids, a large group of secondary plant metabolites ...
Anna T. Germann, Andreas Nakielski, Maximilian Dietsch, Tim Petzel, Daniel Moser, Sebastian Triesch, Philipp Westhoff, Ilka M. Axmann   +7 more
doaj   +1 more source