Results 61 to 70 of about 5,720 (201)

What defines response to vagus nerve stimulation in children with drug‐resistant epilepsy? A prospective cohort study from the CONNECTiVOS collaboration

Epilepsia, Volume 66, Issue 10, Page 3700-3715, October 2025.
Abstract Objectives Responsiveness to vagus nerve stimulation (VNS) in children with drug‐resistant epilepsy (DRE) is often defined based on reduction in seizure frequency, typically at the 50% threshold, with limited consideration to the effects of therapy on seizure severity and health‐related quality of life (HRQoL). In the current report, we sought
Farbod Niazi, Karim Mithani, Hrishikesh Suresh, Simeon M. Wong, Ivanna Yau, Lyndsey McRae, Thiemo F. Dinger, James T. Rutka, Ayako Ochi, Hiroshi Otsubo, Shelly Weiss, Lauren Sham, Elizabeth Donner, Vann Chau, Aristides Hadjinicolaou, Philippe Major, Alexander G. Weil, Jignesh Tailor, Taylor J. Abel, Madison Remick, Emefa Akwayena, Dewi Schrader, Robert J. Bollo, Matthew D. Smyth, Diana Aum, Sean Lew, Shelly Wang, Toba Niazi, Jeffrey S. Raskin, Elysa Widjaja, Howard L. Weiner, Nisha Gadgil, Melissa A. LoPresti, Gregory W. Albert, Aria Fallah, Elizabeth Kerr, Mary Lou Smith, Puneet Jain, George M. Ibrahim   +38 more
wiley   +1 more source

Time to prerandomization seizure count design sufficiently assessed the safety and tolerability of perampanel for the treatment of focal seizures

Epilepsia, Volume 66, Issue 9, Page 3207-3218, September 2025.
Abstract Objective In traditionally designed randomized clinical trials of antiseizure medications, participants take a blinded treatment for a prespecified number of weeks, irrespective of continued seizures. The alternative design time to prerandomization monthly seizure count (T‐PSC) allows participants to end the blinded treatment after an ...
Wesley T. Kerr, Leock Y. Ngo, Liang Zhu, Anna Patten, Jocelyn Y. Cheng, Lavanya Biju, Jacqueline A. French   +6 more
wiley   +1 more source

Synergia rodziny i szkoły – niektóre konteksty teoretyczne i praktyka

Horyzonty Wychowania, 2017
CEL NAUKOWY: Celem artykułu jest próba syntetycznego przedstawienia obszarów problemowych i wskazanie zagadnień, jakie pojawiają się na horyzoncie określenia „synergia rodziny i szkoły”.
Danuta Opozda
doaj  

Deep brain stimulation of the centromedian nucleus for drug‐resistant epilepsy in children: Quality‐of‐life and functional outcomes from the CHILD‐DBS registry

Epilepsia, Volume 66, Issue 7, Page 2225-2238, July 2025.
Abstract Objective Deep brain stimulation of the centromedian nucleus of the thalamus (CM‐DBS) is an investigational, off‐label treatment for drug‐resistant epilepsy (DRE) in children. Although emerging evidence supports its safety and efficacy for select indications, the effect of CM‐DBS on quality of life and functional outcomes such as school ...
Karim Mithani, Farbod Niazi, Hrishikesh Suresh, Yousof Alrumayyan, Eriberto R. Rayco, Ayako Ochi, Hiroshi Otsubo, Elizabeth Kerr, Sara Breitbart, Andrea LeBlanc‐Millar, Nisha Gadgil, Jeffrey S. Raskin, Alexander G. Weil, Aristides Hadjinicolaou, Christian Iorio‐Morin, Shelly Weiss, Puneet Jain, Lauren Sham, Elizabeth Donner, Alfonso Fasano, Carolina Gorodetsky, George M. Ibrahim   +21 more
wiley   +1 more source

Teatr w aspekcie literatury polecanej uczniom klas początkowych w Polsce Ludowej (1944–1953)

Konteksty Pedagogiczne, 2020
Opracowanie prezentuje zrekonstruowany obraz funkcjonowania teatru dla najmłodszych oraz aspekt obowiązkowych lektur szkolnych. Obszar badań skupiono na latach 1944–1953 w Polsce Ludowej, z uwzględnieniem tła lat międzywojennych. Jest to czas gwałtownych
Anna Boguszewska
doaj   +1 more source

Wartość, której nie ma w bilansie - wewnętrznie generowana wartość firmy [PDF]

, 2000
In the contemporary theory of organization management the main goal of enterprise is its value maximization. Value however has many aspects, although in the finance sphere we should accept the market value as the least controversial in this context.
Marcinkowska, Monika
core  

Bacillus subtilis HU58 and Bacillus coagulans SC208 Probiotics Reduced the Effects of Antibiotic-Induced Gut Microbiome Dysbiosis in an M-SHIME^® Model

Microorganisms, 2020
Benefits associated with probiotic use have been reported; however, the mechanisms behind these benefits are poorly understood. The effects of a probiotic formulation (MegaDuo™) containing Bacillus coagulans SC208 and Bacillus subtilis HU58 on intestinal
Massimo Marzorati, Pieter Van den Abbeele, Sarah S. Bubeck, Thomas Bayne, Kiran Krishnan, Aicacia Young, Dilip Mehta, Anselm DeSouza   +7 more
doaj   +1 more source

Poszukiwanie synergii poprzez rozwój zewnętrzny na przykładzie rynku medialnego w Polsce [PDF]

, 2005
Competition growth on media market is the cause of its consolidation. Achieving synergy even thought obvious it is difficult and hard to be realized. We know the cases when values of companies after merger were lower then before.
Godzisz, Tomasz
core  

Gut microbiota‐derived trimethylamine‐N‐oxide inhibits SIRT1 to regulate SM22α‐mediated smooth muscle cell inflammation and promote atherosclerosis progression

Journal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Gut microbiota‐derived metabolite TMAO aggravates atherosclerosis by inhibiting SIRT1, leading to the downregulation of SM22α and promoting smooth muscle cell inflammation via the NF‐κB pathway. This study integrates multi‐omics and in vivo validation to uncover novel therapeutic targets in TMAO–SIRT1–SM22α signaling, offering new insights into ...
Yajuan Yin, Mei Wei, Xiufang Jiang, Mei Liu, Xiaocui Shi, Xiao Zhang, Le Wang, Gang Liu, Mingqi Zheng, Fangfang Ma   +9 more
wiley   +1 more source

Waterfronts, public spaces and tourist potential [PDF]

, 2012
Contemporary cities also known as postindustrial cities are created by dynamic urban development. One of the most significant processes is related to waterfront areas and their new public spaces.
Wójcik, Agnieszka
core