Results 191 to 200 of about 9,227,129 (320)

Synergistic impact of depression and osteoporosis on cardiovascular and all-cause mortality: A cohort study based on NHANES data. [PDF]

Medicine (Baltimore)
Qu X, Wang H, Zhang C, Xu X, Yi Y, Deng Q, Jiang J.   +6 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Synergistic Impact of Copper Nanoparticles Functionalized with Magnetic Chitosan on the Enhanced Adsorptive Sequestration of Metformin Diabetic Drug from Environmental Samples. [PDF]

Polymers (Basel)
Al-Ahmary KM, Aljadaani AH, Yakout AA.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Synergistic impact of serum uric acid and ferritin on MAFLD risk: A comprehensive cohort analysis. [PDF]

Sci Rep
Bae M, Kim KM, Jin MH, Yoon JH.
europepmc   +1 more source

Synergistic impact of arbutin and kaempferol-7-O-α-L-rhamnopyranoside from Nephelium lappaceum L. on whitening efficacy and stability of cosmetic formulations. [PDF]

Sci Rep, 2023
Siridechakorn I, Pimpa J, Choodej S, Ngamrojanavanich N, Pudhom K.   +4 more
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

The synergistic impact of "SO-TO-DO" and one-minute preceptor models on skill and knowledge development. [PDF]

Bioinformation
Rukadikar C, Gupta S, Das A, Gangwar A, Singh A, Saiyad S, Mahajan N, Rukadikar A.   +7 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Rituximab synergizes with hydroxyurea or vincristine in the killing of Ramos Burkitt's lymphoma B cell line [PDF]

, 2014
Abulayha, Abdulmunem, Bredan, Amin, Deyab, Mohamed, Elbanani, Abdulrhman, Geriani, Hajer, Lamami, Yosra, Tabal, Salah   +6 more
core   +2 more sources