Results 191 to 200 of about 604,960 (300)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Tools, Training, and Transformation: The Synergistic Impact of Interventional Pulmonary Programs in Pulmonary and Critical Care Fellowship Training. [PDF]

ATS Sch
Lamb C.
europepmc   +1 more source

The synergistic impact of Spirulina and selenium nanoparticles mitigates the adverse effects of heat stress on the physiology of rabbits bucks. [PDF]

PLoS One, 2023
El-Ratel IT, Elbasuny ME, El-Nagar HA, Abdel-Khalek AE, El-Raghi AA, El Basuini MF, El-Kholy KH, Fouda SF.   +7 more
europepmc   +1 more source

Examining Synergistic Impact Of Learning Inputs On Organisation Innovation

Prestige International Journal of Management & IT - Sanchayan, 2013
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Synergistic impact of air pollution and artificial light at night on memory disorders: a nationwide cohort analysis. [PDF]

BMC Public Health
Tao H, Chen G, Wu L, Lou H.
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Synergistic impact of osseointegration and multifunctionality on functionally graded ceramic composites for bone healing applications. [PDF]

Sci Rep
Youness RA, Mostafa EB, Taha MA.
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

The synergistic impact of Spirulina and Sulfate reducing bacteria on lettuce growth in Cadmium contaminated soil. [PDF]

Sci Rep
Seifikalhor M, Latifi M, Nasiri Almanghadim N, Akbar-Tajari Z, Ahangir A, Hassani SB, Soltani N, Sadeghi H, Eghbal E, Fallahi Z, Gruda NS.   +10 more
europepmc   +1 more source