Results 101 to 110 of about 778,777 (287)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Innovation management in the context of the Fourth Industrial Revolution: challenges and opportunities for management

open access: yesУченые записки Российской академии предпринимательства
This scientific article examines the impact of the Fourth Industrial Revolution (Industry 4.0) on innovation management. The potential challenges and opportunities faced by managers in modern business are considered.
V. I. Khabarov, K. V. Lukashin
doaj   +1 more source

IMPACT OF MERGERS AND AMALGAMATION ON THE PERFORMANCE OF INDIAN COMPANIES [PDF]

open access: yes
This paper is an attempt to evaluate the impact of Mergers on the performance of the companies. Theoretically it is assumed that Mergers improves the performance of the company due to increased market power, Synergy impact and various other qualitative ...
Mahesh Kumar Tambi
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

THE MATRIX OF COMPETENCIES AS A TOOL OF ENTREPRENEURSHIP BACHELOR EDUCATION

open access: yesВысшее образование в России, 2017
The article reviews the matrix of competencies use for studying and formation of educational programs in entrepreneurship at bachelor’s degree. The authors examine the problem of standardization in the field of entrepreneurship education in the context ...
Yu. B. RUBIN   +2 more
doaj  

Joint Effect of Working Conditions and Wages on Labor Shortage in Healthcare

open access: yesВестник Кемеровского государственного университета. Серия: политические, социологические и экономические науки
Healthcare quality depends on medical personnel, i.e., motivation, professional burnout, work-life balance, etc. The authors used standard research methods to investigate the relationship between performance, staff turnover, salary, and ...
Nikolay Merkulov, Aleksandr Anisimov
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

National project «Education» of the Russian Federation in the conditions of the modern world

open access: yesПутеводитель предпринимателя
The national project in the field of education at the present moment of time is being developed together with the projects aimed at the development of the health care system, housing construction and agriculture.
V. I. Khabarov, S. V. Bruev
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Formation of consumer loyalty in the field of digital ecosystem products

open access: yesПутеводитель предпринимателя
The article is devoted to studying the importance of increasing customer loyalty for successful business development in the digital era. The author identifies brand equity, customer trust and satisfaction as key factors influencing the level of customer ...
E. I. Khalif, M. V. Rossinskaya
doaj   +1 more source

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