Results 91 to 100 of about 93,971 (295)

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

How Synonymic Taste Words Alter Perceived Taste in American Consumers

Languages
Investigations into crispy and crunchy in American English have demonstrated that these synonymic taste words have differing effects on perceived taste depending on association.
Tamara Marie Johnson, Simone Eveline Pfenninger   +1 more
doaj   +1 more source

Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants

Advanced Science, EarlyView.
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer, Rong Zhu, Manuel Reithofer, Gerhard Stadlmayr, Katharina Stadlbauer, Panchika Prangkio, Christoph Rippel, Markus Hahn, Aniko Eva Kasztner, Stefanie Stohl, Petr Bednar, Daniel Ruzek, David Glück, Robert Tampé, Gordana Wozniak‐Knopp, Yoo Jin Oh, Miriam Klausberger, Peter Hinterdorfer   +17 more
wiley   +1 more source

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai, Yi Wang, Na‐Na Li, Ling Zeng, Renzhong Liu, Xue Li, Cheukfai Li, Xin‐Yu Ma, Wenkui Fu, Yingsen Tang, Jinjin Chen, Ning Liao, Man‐Li Luo   +12 more
wiley   +1 more source

Extracting Synonyms from Bilingual Dictionaries [PDF]

, 2020
We present our progress in developing a novel algorithm to extract synonyms from bilingual dictionaries. Identification and usage of synonyms play a significant role in improving the performance of information access applications.
Karajah, Eman, Jarrar, Mustafa, Shaalan, Khaled, Khalifa, Muhammad   +3 more
core   +1 more source

High species diversity of Phintella and Phintella‐like spiders (Araneae: Salticidae) in Vietnam revealed by DNA‐based species delimitation analyses

Ecology and Evolution
Salticidae (jumping spiders) usually exhibit pronounced sexual dimorphism in adult morphology, particularly body coloration and size and shape of the first legs.
Luong Thi Hong Phung, Yong‐Chao Su, Takeshi Yamasaki, Yi‐Yen Li, Katsuyuki Eguchi   +4 more
doaj   +1 more source

Taxonomic revision of the genus Poa L. (Poaceae: Pooideae: Poeae) in Chile

Gayana: Botanica, 2022
A taxonomic revision of the genus Poa in Chile is given. Forty-two species, 5 subspecies and 5 varieties distributed in 4 subgenera, 15 sections and one informal group “Punapoa” are recognized.
Víctor L. Finot, Robert J. Soreng, Liliana M. Giussani, Florencia R. Sabena, Nicolás Villalobos   +4 more
doaj  

High‐elevation endemic plants predicted to lose habitat from changing climate in Washington State

American Journal of Botany, EarlyView.
Abstract Premise High‐elevation plants face unique challenges from potential climate change impacts that will likely require upslope migration into increasingly smaller suitable habitat. This situation is particularly acute for endemic species that by definition occupy small geographic ranges.
Nicholas L. Gjording, Erik W. Ertsgaard, David E. Giblin, Iris H. Dimpsey, Owen B. Bard   +4 more
wiley   +1 more source

On the Application of "Once a Synonym Always a Synonym" to Binomials [PDF]

Botanical Gazette, 1895
Volume: 20 ; Start Page: 261 ; End Page ...
openaire   +2 more sources

The usage of derivatives synonyms of verbs. [PDF]

, 2009
Derivative synonyms of verbs are the kind of synonyms which have the same root, different derivational affixes and similar or identical lexical meaning.
Žvybaitė, Vilma,
core