Results 61 to 70 of about 11,986,242 (329)

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Adaptive Cartesian meshes for atmospheric single-column models: a study using Basilisk 18-02-16 [PDF]

Geoscientific Model Development, 2018
It is well known that the representation of certain atmospheric conditions in climate and weather models can still suffer from the limited grid resolution that is facilitated by modern-day computer systems.
J. A. van Hooft, S. Popinet, B. J. H. van de Wiel   +2 more
doaj   +1 more source

ENETS standardized (synoptic) reporting for endoscopy in neuroendocrine tumors

Journal of Neuroendocrinology, 2022
AbstractDespite efforts from various endoscopy societies, reporting in the field of endoscopy remains extremely heterogeneous. Harmonisation of clinical practice in endoscopy has been highlighted by application of many clinical practice guidelines and standards pertaining to the endoscopic procedures and reporting are underlined.
Borbath I., Pape U. -F., Deprez P. H., Bartsch D. K., Caplin M., Falconi M., Garcia-Carbonero R., Grozinsky-Glasberg S., Jensen R. T., Arnold R., Ruszniewski P., Toumpanakis C., Valle J. W., O'Toole D., Belli S. H., Castano J. P., Chen J., Costa F. P., Couvelard A., de Herder W. W., Deroose C. M., Dromain C., Faggiano A., Falkerby J., Fazio N., Frilling A., Grande E., Hand P., Hicks R. J., Horsch D., Howe J. R., Kloppel G., Kolarova T., Kos-Kudla B., Koumarianou A., Krejs G. J., Krenning E. P., Krishna B. A., Leyden S., Masui T., Niederle B., Nieveen van Dijkum E. J., Oberg K., Pavel M., Perren A., Prasad V., Ramage J. K., Reed N. S., Rindi G., Gemelli A., Rinke A., Rothmund M., Singh S., Sundin A., Velthuysen M. F. V., Verslype C., Vullierme M. P., Welin S., Wiedenmann B., Zhao H.   +59 more
openaire   +3 more sources

Bridging home, school and community to address educational inequality: Supporting educational trajectories through community bridge work

British Educational Research Journal, EarlyView.
Abstract This paper explores the role of community stakeholders in supporting the educational trajectories of students experiencing socio‐economic disadvantage in the Irish context. Building on international and national policy debates, the study examines how community‐based organisations, statutory services and outreach initiatives work alongside ...
Aoife Joy Keogh, Deirdre McGillicuddy
wiley   +1 more source

Trends in marine species distribution models: a review of methodological advances and future challenges

Ecography, EarlyView.
Correlative species distribution models (SDMs) are quantitative tools in biogeography and macroecology. Building upon the ecological niche concept, they correlate environmental covariates to species presence to model habitat suitability and predict species distributions.
Moritz Klaassen, Tiago A. Marques, Filipe Alves, Marc Fernandez   +3 more
wiley   +1 more source

Wind Data From Radar Echoes [PDF]

, 1953
Series statement on cover: "Technical Report no. 1"Listed in ISWS Publications Catalog (1995, p. 14) as Contract Report no. 1, with the series statement Technical Report no.
Bigler, S.G., Hiser, Homer W.
core  

The Relationship of Coronal Mass Ejections to Streamers [PDF]

, 1999
We have examined images from the Large Angle Spectroscopic Coronagraph (LASCO) to study the relationship of Coronal Mass Ejections (CMEs) to coronal streamers.
Antiochos, Bravo, Brueckner, Chen, Dere, Guo, Howard, Howard, Hundhausen, Illing, K. P. Dere, Kahler, Koutchmy, Low, McAllister, Mikic, N. B. Rich, Pneuman, Prasad Subramanian, R. A. Howard, Steinolfson, Wang, Wu   +22 more
core   +3 more sources

A Synoptic Map of Halo Substructures from the Pan-STARRS1 3π Survey [PDF]

, 2016
We present a panoramic map of the entire Milky Way halo north of δ∼−30∘δ∼−30∘ (∼30 000 deg2), constructed by applying the matched-filter technique to the Pan-STARRS1 3π Survey data set. Using single-epoch photometry reaching to g ∼22, we are sensitive to
E. Bernard, A. Ferguson, E. Schlafly, N. Martin, H. Rix, E. Bell, D. Finkbeiner, B. Goldman, D. Martínez-Delgado, B. Sesar, R. Wyse, W. Burgett, K. Chambers, P. Draper, K. Hodapp, N. Kaiser, R. Kudritzki, E. Magnier, N. Metcalfe, R. Wainscoat, C. Waters   +20 more
semanticscholar   +1 more source

Predicting oxygen thresholds of marine taxa to improve ecological forecasts

Ecography, EarlyView.
Species' ranges are shifting in response to increasing temperature and decreasing oxygen in coastal oceans. Predicting these shifts is limited by information on physiological oxygen thresholds and how they depend on temperature. Here we collate laboratory‐derived measurements of a common oxygen threshold, pcrit, for 148 animal species that span six ...
Timothy E. Essington, James T. Thorson, Curtis Deutsch   +2 more
wiley   +1 more source

Estimation of return dates and return levels of extreme rainfall in the city of Douala, Cameroon

Heliyon
The problem of extreme phenomena with a more precise estimation of their return periods for early warnings, notably to preserve the safety of populations and properties, arises all over the world.
Calvin Padji, Cyrille Meukaleuni, Cyrille Mezoue Adiang, Daniel Bongue, David Monkam   +4 more
doaj   +1 more source