Results 111 to 120 of about 109,526 (310)

Extra-articular synovial chondromatosis of the ankle: Unusual case with radiologic-pathologic correlation. [PDF]

, 2020
Extra-articular synovial chondromatosis is a rare entity in the foot and ankle. We present a case of a 49-year-old female who presented for evaluation of a palpable concern following trauma; which was found to represent synovial chondromatosis. This case
Abraham, John, Dheer, Sachin, Jiang, Wei, Karanjia, Homyar, Schick, Faith, Sullivan, Paul E, Taweel, Nicholas   +6 more
core   +1 more source

Estrés oxidativo y patogenia del daño articular en equinos [PDF]

, 2007
This review describe the sinovial joint and the different structures that are present in the pathogenesis of joint disease, such as synovial membrane, articular cartilage, and synovial fluid.
Adarmes, Héctor, Galleguillos, Marco, Lemaitre, Maximiliano, Letelier, María   +3 more
core   +2 more sources

Tissue Damage in Rheumatoid Arthritis Is Genetically Linked to Low Peptidylglycine Alpha‐Amidating Monooxygenase Activity in Synovial Fibroblasts

Arthritis &Rheumatology, EarlyView.
Objective Both susceptibility to, and severity of, rheumatoid arthritis (RA) is associated with the rs26232 C allele. Our primary aim was to identify the biologic mechanism underlying this association. Methods Expression of surrounding genes was compared among rs26232 genotypes.
Kevin J. Sheridan, Emma R. Dorris, Maria Inês Pimenta, Jemma Falkov, Matthew Fisher, Sam Pledger, Hector Devey, Munitta Muthana, Denis C. Shields, Richard E. Mains, Betty A. Eipper, Christopher D. Buckley, Anthony G. Wilson   +12 more
wiley   +1 more source

The potential role of synovial T‐cell infiltration following knee joint injury in symptoms and progression to osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Identification of osteoarthritis (OA)‐specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune‐cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi, Miriam T Jackson, Cindy C. Shu, Susan M Smith, Margaret M Smith, Sanaa Zaki, Hadrian Platzer, Nils Rosshirt, David Giangreco, Carla R Scanzello, Christopher B Little   +10 more
wiley   +1 more source

Synoviocyte cultures from synovial fluid

Reumatismo, 2011
The study of the pathogenetic mechanisms of rheumatic diseases is in general carried out through "in vitro" systems based on cellular cultures models. The difficulties to achieve fresh human tissue prompted us to develop a simpler method to obtain fibroblast-like synovial cells from synovial fluid (SF).SF was collected from the knees of 5 patients with
SCANU, ANNA, OLIVIERO, FRANCESCA, BRAGHETTO, LUCA, RAMONDA R, LUISETTO, ROBERTO, CALABRESE, FIORELLA, POZZUOLI, ASSUNTA, PUNZI, LEONARDO   +7 more
openaire   +6 more sources

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source

Machine Learning to Predict Remission Between Six and 24 Months in Rheumatoid Arthritis: Insights from the JAK‐pot Collaboration

Arthritis &Rheumatology, Accepted Article.
Objective To develop, externally validate, and simplify a machine‐learning (ML) model to predict remission between six and 24 months in rheumatoid arthritis (RA) patients initiating TNF inhibitors, JAK inhibitors, IL‐6 inhibitors, abatacept, or rituximab, using data from 11 international registries in the JAK‐pot collaboration.
Zubeyir Salis, Denis Mongin, Denis Choquette, Louis Coupal, Catalin Codreanu, Florenzo Iannone, Roberto Caporali, Tore K Kvien, Sella Provan, Ruth Fritsch‐Stork, Dan Nordström, Nina Trokovic, Karel Pavelka, Jakub Závada, Ana Rodrigues, Ziga Rotar, Prodromos Sidiropoulos, Irini Flouri, Céline Lamacchia, Michele Iudici, Delphine Courvoisier, Kim Lauper, Axel Finckh   +22 more
wiley   +1 more source

Inertial and Linear Re-Absorption Effects on a Synovial Fluid Flow Through a Lubricated Knee Joint

Lubricants
This study examines the flow dynamics of synovial fluid within a lubricated knee joint during movement, incorporating the effect of inertia and linear re-absorption at the synovial membrane.
Abdul Majeed Siddiqui, Khadija Maqbool, Afifa Ahmed, Amer Bilal Mann   +3 more
doaj   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

Arthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Comparison of fatty-acid-binding protein 4 and adiponectin levels in infrapatellar fat pad and subcutaneous adipose tissue, synovial fluid and plasma in subjects with knee osteoarthritis [PDF]

, 2013
Conference Theme: Defying the Aging Spine: Our Mission ContinuesConcurrent Free Papers 2 - Basic Science/General Orthopaedics: no. 2.8Introduction: It was recently reported that inflammation is involved in the pathogenesis of osteoarthritis (OA ...
Chiu, KY, Li, T, Song, YQ, Xu, AM, Yan, CH   +4 more
core