Results 141 to 150 of about 1,338,566 (303)

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

Drug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda, Marc Machnik, Mario Thevis, Yohei Minamijima, Gary Ngai‐Wa Leung, Motoi Nomura, Fumiaki Mizobe, Yuhiro Ishikawa, Kazuhiro Kamiya, Pierre‐Louis Toutain   +9 more
wiley   +1 more source

Infrapatellar fat pad adipose tissue-derived macrophages display a predominant CD11c+CD206+ phenotype and express genotypes attributable to key features of OA pathogenesis

Frontiers in Immunology
ObjectivesIn knee osteoarthritis (OA), macrophages are the most predominant immune cells that infiltrate synovial tissues and infrapatellar fat pads (IPFPs).
Patchanika Hengtrakool, Nitigorn Leearamwat, Panjana Sengprasert, Jutamas Wongphoom, Thiamjit Chaichana, Mana Taweevisit, Srihatach Ngarmukos, Srihatach Ngarmukos, Aree Tanavalee, Aree Tanavalee, Tanapat Palaga, Rangsima Reantragoon, Rangsima Reantragoon, Rangsima Reantragoon   +13 more
doaj   +1 more source

Correlation of biochemical markers in temporomandibular synovial fluid with Wilkes classification and arthroscopic findings

The analysis of synovial fluid is crucial for evaluating joint pathologies, providing specific diagnoses, and guiding treatment. However, consensus on synovial fluid analysis in the temporomandibular joint (TMJ) is lacking.
Sen, Óscar de la, Herrero Álvarez, Sonia, Carvalho de Moraes, Luis Otávio, Bertotti, Maité, Mazó Amorós, Carlota, Mérida Velasco, José Ramón, Martín Granizo, Rafael   +6 more
core   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

Composition of allogeneic equine orthobiologics and their repeated intra‐articular administrations

Equine Veterinary Journal, EarlyView.
Abstract Background Orthobiologics such as platelet‐rich plasma (PRP) and alpha‐2‐macroglobulin (A2MG) are increasingly used for equine musculoskeletal injuries. However, their composition and safety with repeated allogeneic intra‐articular administration remain poorly investigated.
Yanne Van Reusel, Sarah Y. Broeckx, Anna Carolo, Marco Patruno, Jonas Steenbrugge, Jimmy Saunders, Enrico Gugliandolo, Jan H. Spaas   +7 more
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source

A Pain in the Buttocks: Practice Article for Sonographically Imaging the Quadratus Femoris and Ischiofemoral Impingement

Journal of Clinical Ultrasound, EarlyView.
Hip external rotation can cause compression of the quadratus femoris (QF) between the ischial tuberosity and lesser trochanter of the femur, resulting in pain in the buttock, hip, and groin which can radiate down the leg. Ultrasound imaging can demonstrate dynamic impingement of the QF, including symptom provocation.
Elaine Tyzack, Michelle Fenech
wiley   +1 more source

Recent Advances in Synovial Fluid Analysis [PDF]

, 1974
Synovial fluid analysis is a frequently ignored examination except in suspected cases of septic conditions. It has been shown that it is an extremely valuable procedure in making rapid and accurate diagnoses in many types of joint ...
Owen, Duncan S., Jr.
core  

Old disease, new twist

Journal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source