Results 171 to 180 of about 1,268,728 (291)

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

open access: yesThe FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah   +5 more
wiley   +1 more source

Use of an Oral Health‐Related Quality of Life Instrument to Measure Unmet Dental Care Needs in Adults With Inherited Bleeding Disorders

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Preventive dental care is vital for individuals with bleeding disorders to reduce the need for potentially invasive procedures. Although dental care is a mandated function of U.S. federally supported hemophilia treatment centers (HTCs), access to dental care is widely variable.
Miguel A. Escobar   +4 more
wiley   +1 more source

Can we identify which patients are likely to have septic arthritis with borderline synovial fluid cell counts? [PDF]

open access: yesJ Bone Jt Infect
Liu B   +6 more
europepmc   +1 more source

Increased Levels of Inflammatory Proteins, Including TARC/CCL17, in Skin of AD Patients During JAK Inhibitor Treatment

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 260-263, March 2025.
Celeste M. Boesjes   +7 more
wiley   +1 more source

Prevalence and Risk Factors of Systemic Lupus Erythematosus in Patients With Chronic Cutaneous Lupus: A Bicentric Study Employing Three Classification Criteria

open access: yesInternational Journal of Dermatology, EarlyView.
This bicentric study of 95 CCLE patients shows SLE prevalence (21.1%–31.6%) varies significantly by classification criteria. Arthralgia was a consistent independent risk factor across all systems. Our findings support the implementation of systematic risk‐stratified screening protocols for CCLE patients, with particular attention to joint symptoms and ...
Noureddine Litaiem   +4 more
wiley   +1 more source

Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications

open access: yesImmunology, EarlyView.
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang   +9 more
wiley   +1 more source

Large-scale molecular endotype discovery in synovial fluid reveals osteoarthritis as a single biological continuum. [PDF]

open access: yesNat Commun
Perry TA   +23 more
europepmc   +1 more source

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