Results 231 to 240 of about 109,526 (310)

Personalized Cancer Vaccines in the Clinical Trial Pipeline

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 362-368, June 2026.
ABSTRACT Aim To present an overview of personalized cancer vaccines currently undergoing clinical development, aiming to enhance awareness and promote collaboration among academic, commercial researchers, and non‐profit communities. Methods A dataset of 78 clinical trials for personalized cancer vaccines was generated using ClinicalTrials.gov database ...
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

Resident synovial macrophages in synovial fluid: Implications for immunoregulation. [PDF]

Clin Immunol
Cyndari KI, Scorza BM, Zacharias ZR, Pessôa-Pereira D, Strand L, Mahachi K, Oviedo JM, Gibbs L, Butler KL, Ausdal G, Hendricks D, Yahashiri R, Elkins JM, Gulbrandsen T, Peterson AR, Willey MC, Fairfax KC, Petersen CA.   +17 more
europepmc   +1 more source

The “Tianyu” Formulation Alleviates Rheumatoid Arthritis by Modulating the NLRP3/Caspase‐1/GSDMD‐Mediated Pyroptosis Pathway

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Proposed signaling pathway by which TY modulates NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis. ABSTRACT This research focuses on exploring the modulation of pyroptosis and its underlying mechanisms via the “Tianyu” formulation (TY), a traditional Chinese medicine, in human rheumatoid arthritis fibroblast‐like synovial cells (RA‐HFLS) and a collagen ...
Yueya Zhu, Xinying Cai, Qiuhan Zheng, Chunqiu Fang, Zhi Pan, Yinghang Wang   +5 more
wiley   +1 more source

Effects of pentosan polysulfate sodium on synovial fluid biomarkers in moderate to severe knee osteoarthritis: an exploratory, phase 2, randomized, double-blind, placebo-controlled trial. [PDF]

Arthritis Res Ther
Skerrett DL, Stapledon CJM, Ahuja M, Navuru DR, Duiker MJ, Krishnan R, Schnitzer TJ, Peat RA, Bloom PD.   +8 more
europepmc   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

The metallophore staphylopine is essential for survival of Staphylococcus epidermidis in human synovial fluid

Sims L, Yasir M, Manners E, Hill C, Felgate H, Wain J, McNamara I, Webber MA.   +7 more
europepmc   +1 more source

Elevated Serum Proadrenomedullin Levels in Rheumatoid Arthritis Versus Spondyloarthritis: Insights From a Biobank Cohort

ACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective Proadrenomedullin (pro‐ADM) is a peptide implicated in immunomodulation, with higher levels observed in inflammatory conditions, cardiovascular impairment, and sepsis. Although extensively studied in acute disorders, its potential as a biomarker in inflammatory arthritis remains underexplored.
Nefeli Stavroula Papastathopoulou, Elisa Assirelli, Simona Neri, Susanna Naldi, Jacopo Ciaffi, Luana Mancarella, Veronica Brusi, Lucia Lisi, Federica Pignatti, Piero Ruscitti, Francesco Ursini   +10 more
wiley   +1 more source

Synovial Fluid-derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP-1 Signaling Pathway. [PDF]

Adv Sci (Weinh)
Chen T, Zeng Q, Xu T, Qi X, Li K, Wei J, Hao L.   +6 more
europepmc   +1 more source