Results 151 to 160 of about 135,885 (308)
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
iNew Medicine, EarlyView.The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang +4 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang +10 more
wiley +1 more source
The Potential Role of Hepatocyte Growth Factor in Degenerative Disorders of the Synovial Joint and Spine. [PDF]
Int J Mol Sci, 2020 Tonomura H +5 more
europepmc +1 more source
Knee arthroplasty failure is associated with significant systemic multimetal exposure
Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.Abstract Purpose This study investigated whether patients scheduled for revision total knee arthroplasty (TKA) are systemically exposed to arthroplasty metals, and whether systemic metal levels in these patients differ depending on the implants' levels of constraint.
Anna Flindt +8 more
wiley +1 more source
Acta Biomedica Scientifica, 2013 The purpose of this study was comparative analysis of normal biochemical composition of synovial fluid of knee and elbow human joints. Studies were performed on synovial fluid samples of 33 cadavers of suddenly dead people of both sexes (26 men and.
E. S. Spirkina +2 more
doaj
Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.Abstract Purpose To evaluate the safety and efficacy of intra‐articular autologous transplantation of adipose‐derived connective tissue micrografts rich in stromal vascular fraction (CTM‐SVF), obtained using an enzyme‐free system (Hy‐Tissue® SVF) for knee osteoarthritis (OA). Methods Thirty patients (mean age of 53.3 ± 6.4 years) with Kellgren–Lawrence
Laura Mangiavini +11 more
wiley +1 more source