Results 41 to 50 of about 135,885 (308)

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez   +12 more
wiley   +1 more source

MicroRNA-29a Counteracts Synovitis in Knee Osteoarthritis Pathogenesis by Targeting VEGF

open access: yesScientific Reports, 2017
Synovitis contributes to the development of osteoarthritis (OA) of the knee. MicroRNAs regulate joint microenvironment homeostasis and deterioration. This study was undertaken to characterize the actions of microRNA-29a (miR-29a) to synovial remodeling ...
Jih-Yang Ko   +6 more
doaj   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

open access: yesArthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier   +12 more
wiley   +1 more source

Wear Tests of a Potential Biolubricant for Orthopedic Biopolymers [PDF]

open access: yes, 2015
Most wear testing of orthopedic implant materials is undertaken with dilute bovine serum used as the lubricant. However, dilute bovine serum is different to the synovial fluid in which natural and artificial joints must operate. As part of a search for a
Black   +6 more
core   +2 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

Coupling mechanism of bioinspired artificial composite synovial fluid on the tribological behavior of artificial joints

open access: yesFriction
Changes in the components of synovial fluid in the human body have an important influence on the tribological behavior of artificial joints. Based on the concentration of components in the synovial fluid after arthroplasty, “hard−soft” joint pair ...
Jiajia Cen   +7 more
doaj   +1 more source

In vivo mechanotransduction: Effect of acute exercise on the metabolomic profiles of mouse synovial fluid

open access: yesOsteoarthritis and Cartilage Open, 2022
Objective: Exercise is known to induce beneficial effects in synovial joints. However, the mechanisms underlying these are unclear. Synovial joints experience repeated mechanical loading during exercise.
Alyssa K. Hahn   +5 more
doaj   +1 more source

The effect of robenacoxib on the concentration of C-reactive protein in synovial fluid from dogs with osteoarthritis [PDF]

open access: yes, 2013
Background: Robenacoxib is a novel and highly selective inhibitor of COX-2 in dogs and cats and because of its acidic nature is regarded as being tissue-selective.
Bennett, David   +6 more
core   +2 more sources

Biology of the synovial joint. [PDF]

open access: yesAnnals of the Rheumatic Diseases, 2000
Biology of the synovial joint. Eds C W Archer, B Caterson, M Benjamin, J R Ralphs. (Pp 443; £70.) Amsterdam: Harwood Academic Publishers, 1999. ISBN 90-5702-327-X. Biology of the Synovial Joint grew out of a symposium held during the summer of 1996 at the University of Wales in Cardiff. The editors convened that meeting in the “belief that joints need
openaire   +2 more sources

Multi‐Responsive Dendrimer‐Hyaluronic Acid Hydrogel With Lubricating and Immunoregulatory Functions for Synergistic Osteoarthritis Therapy

open access: yesAdvanced Functional Materials, EarlyView.
A hydrogel with dynamic cross‐links was formed by cross‐linking hyaluronic acid with curcumin‐preloaded, phenylboronic acid‐modified poly(amidoamine) dendrimers. This hydrogel exhibited excellent injectability and self‐healing ability, enabling controlled Cur release in response to low pH, high reactive oxygen species (ROS) generation, or mechanical ...
Junjie Liu   +9 more
wiley   +1 more source

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