Results 101 to 110 of about 46,096 (291)

Mitochondrial dynamics in autoimmune diseases

open access: yesRheumatology &Autoimmunity, EarlyView.
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma   +5 more
wiley   +1 more source

The Role of Synovial Membrane in the Development of a Potential In Vitro Model of Osteoarthritis. [PDF]

open access: yesInt J Mol Sci, 2022
Harvanova D   +8 more
europepmc   +1 more source

Clustering of Membrane Receptors: Insights from DNA Origami‐Based Approaches

open access: yesSmall, EarlyView.
Receptor clustering critically influences cell signaling, yet its precise regulation remains elusive. This review highlights how DNA origami structures serve as nanoscale tools to uncover receptor organization and provide new insights into signal transduction.
Carmen M. Domínguez   +1 more
wiley   +1 more source

Kartogenin‐Loaded Aminated Hollow Mesoporous Prussian Blue Nanozyme‐Reinforced Hydrogel Remodels the Senescent Microenvironment via Reactive Oxygen Species Scavenging and Stimulator of Interferon Genes Inhibition to Promote Cartilage Regeneration

open access: yesSmall Structures, EarlyView.
This study successfully develops an injectable, dual‐function nanocomposite hydrogel comprising kartogenin‐loaded aminated hollow mesoporous Prussian blue (NH2‐HMPB) nanozyme (termed NH@K nanozyme) and hyaluronic acid methacrylate (HAMA). NH@K nanozyme rejuvenates the senescent microenvironment by scavenging reactive oxygen species and inhibiting ...
Shu‐Hang He   +10 more
wiley   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

open access: yesVIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma   +6 more
wiley   +1 more source

Increase in CD5L expression in the synovial membrane of knee osteoarthritis patients with obesity. [PDF]

open access: yesCent Eur J Immunol, 2021
Shoji S   +9 more
europepmc   +1 more source

Gastric dilatation secondary to incarceration through a gastrosplenic omental rent in a dog

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 2‐year‐old, entire, female Dogue de Bordeaux presented with inappetence and abdominal distension. Radiographs revealed gastric dilatation and malpositioning. Given the absence of classical signs of gastric dilatation and volvulus, a medical approach was elected. After 24 hours, the dog's condition deteriorated.
Clara Galvani   +4 more
wiley   +1 more source

Infrapatellar Fat Pad-Synovial Membrane Anatomo-Fuctional Unit: Microscopic Basis for Piezo1/2 Mechanosensors Involvement in Osteoarthritis Pain. [PDF]

open access: yesFront Cell Dev Biol, 2022
Emmi A   +10 more
europepmc   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen   +5 more
wiley   +1 more source

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