Results 221 to 230 of about 90,784 (291)

SIRT1 Downregulation by Advanced Glycation End Products Activates RANKL‐Dependent Osteoclast Signaling and Drives Chondrocyte Senescence During Osteoarthritis Development

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Mechanistic study of AGEs‐induced OA progression via SIRT1/RANKL/RANK signaling‐mediated osteoclast–chondrocyte communication and cellular senescence. ABSTRACT Advanced glycation end products (AGEs) accumulate with aging and metabolic stress and are increasingly implicated in osteoarthritis (OA) pathology.
Yizhou Li   +4 more
wiley   +1 more source

Successful repair of a carpal sheath synovial hernia using a polypropylene mesh

open access: yesEquine Veterinary Education, Volume 38, Issue 5, Page e228-e234, May 2026.
Summary A cob‐cross mare presented with a carpal sheath synovial hernia on the distolateral antebrachium following carpal sheath tenoscopy to treat a radial physeal exostosis and deep digital flexor tendon injury. The presumed source of pain was the weakened skin over the hernia as the intrathecal pathology identified at the initial tenoscopy had ...
S. R. L. Neild   +3 more
wiley   +1 more source

Fatal spinal cord compression in a horse with chronic actinobacterial cranial nuchal bursitis

open access: yesEquine Veterinary Education, Volume 38, Issue 5, Page e235-e242, May 2026.
Summary A 14‐year‐old warmblood gelding was managed for waxing and waning cranial nuchal bursitis for 2 years. Intensive medical and surgical management was not curative, and the patient was subjected to euthanasia after becoming acutely recumbent. Ante‐mortem and post‐mortem next generation sequencing of bursal tissue and post‐mortem conventional PCR ...
H. Mesch   +4 more
wiley   +1 more source

Human Synovia Contains Trefoil Factor Family (TFF) Peptides 1-3 Although Synovial Membrane Only Produces TFF3: Implications in Osteoarthritis and Rheumatoid Arthritis. [PDF]

open access: yesInt J Mol Sci, 2019
Popp J   +10 more
europepmc   +1 more source

Equine experimental lameness induction models

open access: yesEquine Veterinary Education, Volume 38, Issue 5, Page 270-284, May 2026.
Summary Equine lameness due to musculoskeletal injury remains a common and significant cause of decreased performance. While our understanding and management of lameness have improved with advanced imaging, as well as diagnostic and therapeutic progression, a need for experimental equine models of lameness remains.
A. Dockery, B. Beasley, V. J. Moorman
wiley   +1 more source

Correction to: Culture of mesenchymal stem cells derived from equine synovial membrane in alginate hydrogel microcapsules. [PDF]

open access: yesStem Cell Res Ther, 2018
Santos VH   +8 more
europepmc   +1 more source

Therapeutic potential of mesenchymal stem cells in peripheral nerve injuries in horses

open access: yesEquine Veterinary Education, Volume 38, Issue 5, Page 252-260, May 2026.
Summary Peripheral nerve injuries (PNI) in horses represent a significant clinical challenge, frequently associated with functional deficits and reduced athletic performance. Conventional therapeutic approaches, primarily based on anti‐inflammatory treatments and rehabilitation, offer limited efficacy, driving the search for innovative alternatives. In
L. V. de Oliveira Ferreira   +1 more
wiley   +1 more source

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