Results 271 to 280 of about 91,327 (332)
Objective To assess the relationship of circulating and synovial immune cells with synovial molecular pathology and disease outcomes in patients with early rheumatoid arthritis (RA). Methods Patients with early (<12 months) treatment‐naive RA (n = 144) from the Pathobiology of Early Arthritis Cohort were included in this post hoc analysis.
Felice Rivellese +13 more
wiley +1 more source
Gout and NLRP3 Inflammasome Biology
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley +1 more source
ABSTRACT Tumor Necrosis Factor‐alpha (TNF‐α) inhibitors have been successfully used to treat rheumatoid arthritis (RA), psoriatic and ankylosing arthritis, and inflammatory bowel disease. While these inhibitors effectively decrease the inflammatory activity of immune‐related disorders, they have been associated with central nervous system (CNS) and ...
Shahla Mohammed Saeed Rasul +3 more
wiley +1 more source
Correction to: Culture of mesenchymal stem cells derived from equine synovial membrane in alginate hydrogel microcapsules. [PDF]
Santos VH +8 more
europepmc +1 more source
Kaplan Lesion in a 10‐Year‐Old Boy: A Case Report
ABSTRACT Kaplan's lesion, a rare complex metacarpophalangeal (MCP) joint dislocation in children, is often requires surgical intervention. The dorsal approach minimizes neurovascular risk, while the volar approach allows volar plate repair. A 10‐year‐old boy presented with a left index finger MCP dislocation after trauma.
Kushal Khanal +6 more
wiley +1 more source
Culture of mesenchymal stem cells derived from equine synovial membrane in alginate hydrogel microcapsules. [PDF]
Santos VH +8 more
europepmc +1 more source
Telomere–metabolism–immunity axis in sarcoma: Immune evasion mechanisms and therapeutic strategies
Telomere maintenance mechanisms (telomerase reverse transcriptase and alternative lengthening of telomeres) reprogram metabolism and dampen innate immune sensing in sarcomas. Metabolic rewiring (glutamine addiction, glycolysis and fatty acid oxidation) fosters T‐cell dysfunction and myeloid‐derived suppressor cell accumulation.
Ji‐Yong Sung, June Hyuk Kim
wiley +1 more source
This review discusses the principles underlying the interplay of epigenetics, metabolism, and post‐transcriptional regulation of gene expression mediated by RNA‐binding proteins, both in the nucleus and in the cytoplasm. Particularly, it focuses on the relevance that these circuits have in lymphocytes and autoimmunity.
Francesca Rossi, Martin Turner
wiley +1 more source
Osteochondral repair with synovial membrane‑derived mesenchymal stem cells. [PDF]
Li H, Qian J, Chen J, Zhong K, Chen S.
europepmc +1 more source

