Results 281 to 290 of about 91,327 (332)

LILRA5 Functions to Induce ROS Production on Innate Immune Cells

open access: yesEuropean Journal of Immunology, Volume 55, Issue 10, October 2025.
Ligation of the activating LILRA5 receptor specifically stimulates ROS production by monocytes and neutrophils. Though LILRA5 transcripts are upregulated upon immune stimulation, surface LILRA5 expressions are dynamically regulated. Enhanced soluble LILRA5 was observed during immune challenge, suggesting that dynamic regulation of LILRA5 modulates ROS ...
Zuyi Fu   +13 more
wiley   +1 more source

CD40LG as a Biomarker in Rheumatoid Arthritis: Links to Bone Destruction and Interstitial Lung Disease ‐ A Bioinformatic Analysis With Clinical Validation

open access: yesHealth Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Biomarkers are essential tools in the diagnosis and management of various diseases. Rheumatoid arthritis (RA) is a systemic inflammatory disorder that frequently results in damage to joints and organs. Here, we examined potential biomarkers and therapeutic agents for RA patients.
Chuanhui Yao   +10 more
wiley   +1 more source

The promising potential of intra‐articular losartan combined with scaffold implantation for osteochondral repair: a comparative study in a rabbit model against osteochondral autograft transplantation

open access: yesJournal of Experimental Orthopaedics, Volume 12, Issue 4, October 2025.
Abstract Purpose This study aimed to compare the radiological, macroscopic, biomechanical and histological outcomes of osteochondral autograft transplantation (OAT) and a combination of intralesional scaffold with intra‐articular losartan injection in a rabbit model of osteochondral injury.
Mesut Ok   +7 more
wiley   +1 more source

The cytokine expression in synovial membrane and the relationship with pain and pathological findings at hip arthroscopy. [PDF]

open access: yesJ Exp Orthop, 2017
Fukushima K   +8 more
europepmc   +1 more source

Spatial Distribution of Extracellular Vesicles, Autofluorescence and CD9 Positivity Around Chondrocytes in the Superficial Layer of Articular Cartilage

open access: yesJournal of Extracellular Vesicles, Volume 14, Issue 10, October 2025.
ABSTRACT This study investigates the distribution of extracellular vesicles (EVs) in superficial articular cartilage, hypothesizing that EVs (a) are unevenly distributed in this zonally organized tissue and (b) share a pattern similar to tissue autofluorescence.
Florian Gellhaus   +7 more
wiley   +1 more source

Chitosan/Platelet‐Rich Plasma Implants in an Ovine Arthroscopic Model of Meniscus Repair

open access: yesJournal of Orthopaedic Research, Volume 43, Issue 10, Page 1875-1886, October 2025.
ABSTRACT Despite the availability of various repair techniques, many meniscal tears remain irreparable. A freeze‐dried chitosan‐based formulation reconstituted in autologous platelet‐rich plasma has shown potential in preclinical studies for enhancing suture‐based meniscus repair.
Margaux Delvaux   +6 more
wiley   +1 more source

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