Results 71 to 80 of about 29,165 (230)

Primary intrathoracic malignant mesenchymal tumours: computed tomography features of a rare group of chest neoplasms [PDF]

, 2014
OBJECTIVES: To describe the computed tomography (CT) features in a case series of primary intrathoracic extracardiac malignant mesenchymal tumours (sarcomas). METHODS: A 5-year retrospective research was conducted, and 18 patients were selected. CT exams
Claus Peter Heussel, Gregor Sommer, Hans-Ulrich Kauczor, Marcel Koenigkam-Santos, Michael Puderbach, Philipp Albert Schnabel, Seyer Safi   +6 more
core   +1 more source

Impaired angiogenesis in gestational diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation

The Journal of Physiology, EarlyView.
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid, Francisco Algaba‐Chueca, Elsa Maymó‐Masip, Mónica Ballesteros, Montse Inglés, Albert Guarque, Nerea Vilanova‐Ricart, Ariadna Prats, Azra Kulovic‐Sissawo, Elisa Weiss, Ursula Hiden, Joan Vendrell, Sonia Fernández‐Veledo, Ana Megía   +13 more
wiley   +1 more source

Synovial sarcoma with intra-abdominal metastasis causing hemoperitoneum: a case-report

World Journal of Surgical Oncology, 2023
Synovial sarcoma is a rare soft tissue sarcoma which frequently involves the upper or lower extremities. Soft tissue sarcomas including synovial sarcoma have a propensity to metastasize to the lungs, and there are very few reports of metastatic lesions ...
Joshua J. Thompson, Rachel A. Koch, Vicki L. Keedy, Deepa R. Magge   +3 more
doaj   +1 more source

Sarcoma sinovial en el perro : 2 casos clínicos [PDF]

, 1995
Dos casos de sarcoma sinovial fueron diagnosticados en dos Rottweiler mediante biopsias sinoviales. Se describen los signos clínicos y radiográficos, así como las características histopatológicas del tumor y del líquido sinovial.Two cases of synovial ...
Chico, A, Durall Rivas, Ignacio, Martí, J. M., Menes, I.   +3 more
core  

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Na⁺ entry through heteromeric TRPC4/C1 channels mediates (-)Englerin A-induced cytotoxicity in synovial sarcoma cells [PDF]

, 2017
The sesquiterpene (-)Englerin A (EA) is an organic compound from the plant Phyllanthus engleri which acts via heteromeric TRPC4/C1 channels to cause cytotoxicity in some types of cancer cell but not normal cells. Here we identified selective cytotoxicity
A Batova, A Beck, A Greka, A Riccio, AL Jackson, BC Fuchs, C Carson, C Sourbier, C Sourbier, CE Herzog, EL Spurrell, FJ Sulzmaier, H Al-Hussaini, H Suzuki, HN Rubaiy, J Myeong, J Myeong, JE Camacho Londono, JM David, JM Richter, KN Westlund, M Miller, MJ Ludlow, N Utsunomiya-Tate, R Ratnayake, RT Williams, T Rodrigues, U Storch, V Caropreso, VV Tsvilovskyy, Y Akbulut, Y Itoh, Z Wu   +32 more
core   +3 more sources

Personalized Cancer Vaccines in the Clinical Trial Pipeline

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 362-368, June 2026.
ABSTRACT Aim To present an overview of personalized cancer vaccines currently undergoing clinical development, aiming to enhance awareness and promote collaboration among academic, commercial researchers, and non‐profit communities. Methods A dataset of 78 clinical trials for personalized cancer vaccines was generated using ClinicalTrials.gov database ...
Liudmila Iamukova, Elena Alferova
wiley   +1 more source

Thyroid Synovial Sarcoma: A Case Report

Acta Medica Iranica, 2013
Sarcomas are rare tumors account for about 1% of cancers in adult. Soft tissue sarcomas are the most common one. Synovial sarcoma's incident is about 10% of all sarcomas and most commonly rise from para-articular regions in young adults.
Ali Ghafouri, Taha Anbara, Ali Mir, Marzieh Lashkari, Mohammad Nazari   +4 more
doaj   +2 more sources

The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma. [PDF]

, 2016
Expression of the SS18/SYT-SSX fusion protein is believed to underlie the pathogenesis of synovial sarcoma (SS). Recent evidence suggests that deregulation of the Wnt pathway may play an important role in SS but the mechanisms whereby SS18-SSX might ...
Aguet, M., Cironi, L., Cornaz, S., Fernandes Vieira, V., Fregni, G., Fusco, C., Letovanec, I., Petricevic, T., Provero, P., Stamenkovic, I.   +9 more
core   +3 more sources