Results 151 to 160 of about 52,925 (287)

Sustained Hypoxia‐Inducible Factor 1‐Alpha Accumulation Disrupts the Articular Niche to Promote Osteoarthritis Pathogenesis

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
Sustained HIF‐1α accumulation is not a compensatory shield, but a potent pathogenic driver of osteoarthritis. Continuous HIF‐1α signaling physically eradicates the avascular cartilage niche and primes the synovium for inflammation, establishing HIF‐1α as a critical target for disease‐modifying therapies.
Weiyuan Gong   +15 more
wiley   +1 more source

The association of CT-detected intra-articular calcification with MRI-detected effusion-synovitis and Hoffa-synovitis in knee OA: The Multicenter Osteoarthritis study. [PDF]

open access: yesOsteoarthritis Cartilage
Liew JW   +10 more
europepmc   +1 more source

Needle bevel orientation does not affect diffusion of contrast medium during perineural injection of the lateral palmar/plantar nerve and lateral palmar metacarpal/plantar metatarsal nerves

open access: yesEquine Veterinary Education, Volume 38, Issue 7, Page e456-e463, July 2026.
Summary Background Perineural anaesthesia is used to localise pain in horses presenting with lameness. Diffusion of local anaesthetics during perineural analgesia complicates clinical interpretation. Needle bevel orientation has been shown to affect drug diffusion in humans.
V. Knopp   +6 more
wiley   +1 more source

The Role of Musculoskeletal Ultrasound in Psoriatic Arthritis: From Preclinical Detection to Treatment Monitoring. [PDF]

open access: yesCurr Rheumatol Rep
D'Ignazio E   +10 more
europepmc   +1 more source

Distal interphalangeal joint capsule enthesopathy of the middle phalanx and articular cartilage loss

open access: yesEquine Veterinary Journal, Volume 58, Issue 4, Page 1041-1048, July 2026.
Abstract Background Significant distal interphalangeal joint (DIPJ) pathology, particularly affecting soft tissue and articular cartilage, is often not identifiable on radiographs but can be accompanied by joint capsule enthesopathy on the middle phalanx (P2), which can be readily identified.
Monika A. Samol   +2 more
wiley   +1 more source

Bio‐Propelled Stomatocyte Nanomotors with Glutathione‐Responsiveness for Osteoarthritis Treatment

open access: yesAngewandte Chemie, Volume 138, Issue 23, 1 June 2026.
Glutathione (GSH)‐responsive stomatocyte nanomotors with encapsulated MTX utilize oxygen to achieve autonomous motion and undergo GSH‐induced dissociation, enhancing cellular uptake, tissue penetration, and MTX release within the osteoarthritis (OA) region, thereby improving therapeutic efficacy.
Jianhong Wang   +12 more
wiley   +2 more sources

Magnetic resonance imaging of hand involvement in polymyalgia rheumatica: a comparison with seropositive rheumatoid arthritis. [PDF]

open access: yesRMD Open
Fruth M   +5 more
europepmc   +1 more source

Chronic ulcerative oesophagitis rich in IgG4‐positive plasma cells – a distinct clinicopathological entity

open access: yesHistopathology, Volume 89, Issue 1, Page 47-57, July 2026.
We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger   +5 more
wiley   +1 more source

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