Results 71 to 80 of about 44,666 (201)

Distinct late-stage osteoarthritis profiles identified through NF-κB, TNF-α, and TGF-β–driven synovial inflammation and pain

Scientific Reports
This study delineates distinct late-stage osteoarthritis (OA) profiles, characterized by NF-κB, TNF-α, and TGF-β–mediated synovial inflammation and pain, in a cohort of 31 patients undergoing joint arthroplasty.
Sofija Semenistaja, Liba Sokolovska, Simons Svirskis, Peteris Studers, Valerija Groma, Sandra Skuja   +5 more
doaj   +1 more source

Increased Plasma Microbial tDR‐1 in At‐Risk Individuals Is Associated With Decreased Conversion to Clinical Rheumatoid Arthritis and Reduces an In Vitro Macrophage Type 1 Interferon Response

Arthritis &Rheumatology, EarlyView.
Objective Microbial small RNAs can regulate human genes. Higher plasma concentrations of microbial transfer RNA (tRNA)‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anticyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (
Anastasiia Phothisane, Tulsi K. Joishy, Carolina Ramirez‐Becerra, Qiong Wu, Jennifer Seifert, Marie L. Feser, Jill M. Norris, M. Kristen Demoruelle, LauraKay Moss, Kevin D. Deane, V. Michael Holers, Michelle J. Ormseth   +11 more
wiley   +1 more source

Pigmented Villonodular Synovitis Causing Osteonecrosis of the Femoral Head: A Case Report

Case Reports in Orthopedics, 2013
We report a case of a 27-year-old man with pigmented villonodular synovitis of the hip joint with coincident osteonecrosis of the femoral head. According to our review of the English-language literature, no detailed report of osteonecrosis of the femoral
Tomohiro Mimura, Taku Kawasaki, Keitaro Yagi, Kanji Mori, Shinji Imai, Yoshitaka Matsusue   +5 more
doaj   +1 more source

Arthroscopic Implantation of Minced Cartilage From the Os Trigonum and Posterolateral Process of the Talus: Single‐Stage Cell‐Based Treatment of Osteochondral Lesion of the Talus

Arthroscopy Techniques, EarlyView.
Abstract The best surgical treatment of osteochondral lesion of the talus (OLT) remains controversial. Among the available surgical procedures for OLTs, implantation of the minced cartilage from the talar lesion is a promising cell‐based technique. However, surgeons may experience difficulties when enough volume and quality of the cartilage cannot be ...
Hélder Pereira, Takuji Yokoe
wiley   +1 more source

Imaging-based measures of synovitis in knee osteoarthritis: A scoping review and narrative synthesis

Osteoarthritis and Cartilage Open
Background: Synovitis has emerged as a tissue target of importance in OA research and is commonly evaluated with medical imaging. Objectives: The purpose of this scoping review was to identify and describe the medical imaging techniques and definitions ...
Robert S. Dima, Trevor B. Birmingham, Mary-Ellen Empey, C. Thomas Appleton   +3 more
doaj   +1 more source

Extracellular Matrix With Bone Marrow Aspirate Concentrate for Osteochondritis Dissecans of the Capitellum in Adolescents

Arthroscopy Techniques, EarlyView.
Abstract Capitellar osteochondritis dissecans is most frequently encountered in overhead and tumbling adolescent athletes. Traditional management with abrasion chondroplasty or microfracture results in fibrocartilage formation and variable return to sport rates, whereas osteochondral autograft transfer system or osteochondral allograft transplantation ...
Joshua T. Bram, Nicolas Pascual‐Leone, Nathan H. Varady, Colson Zucker, Peter D. Fabricant   +4 more
wiley   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science
Gut microbiota dysbiosis and associated host immuno‐metabolic disorders may play a role in knee synovitis. Herein, integrated multi‐omics analyses of stool and blood samples from subjects from Pearl River Osteoarthritis Cohort (PROC, N = 207) are ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
doaj   +1 more source

Arthroscopic Osteochondral Fragment Fixation of the Medial Femoral Condyle Using Knotless Suture Anchors

Arthroscopy Techniques, EarlyView.
Abstract Fixation of unstable osteochondral joint fragments is vital to long‐term joint function, but there are various repair techniques in the literature. This technical note describes a suture bridge technique performed arthroscopically that reduces the potential for future complications post operatively while stabilizing an osteochondral fracture ...
Molly N. Jones, Jeffton Pierre, Patrick Ryan, Clayton W. Nuelle, Steven F. DeFroda   +4 more
wiley   +1 more source

Clinical Images: Skeletal fluorosis presenting with diffuse periostitis and polyarticular synovitis

Arthritis &Rheumatology, EarlyView.
Mitali Sen
wiley   +1 more source

Posterolateral Portal Use During Hip Arthroscopy for Resection of Posterior Hip Cysts

Arthroscopy Techniques, EarlyView.
Abstract Hip arthroscopy is a widely accepted, minimally invasive technique for treating various hip joint disorders. The traditional approach typically involves the supine position with traction and an anterolateral entry point. However, this approach presents challenges, including insufficient exposure of posterior hip lesions and an increased risk ...
Peng Chen, Yueyang Tian, Jiang Guo, Peng Zhang, Jingtao Huang, Hongxin Zhuo, Xintao Zhang   +6 more
wiley   +1 more source