Results 71 to 80 of about 52,925 (287)

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Simultaneous involvement of pigmented villonodular synovitis in the left shoulder glenohumeral joint and ankle joint: a rare case report

BMC Musculoskeletal Disorders
Background Pigmented Villonodular Synovitis, although uncommon, can lead to significant joint destruction if not diagnosed and treated early. Concurrent polyarticular presentation in adults is exceedingly rare, appearing in less than 1% of cases.
Bo-Kyung Suh, Jinhwa Jeong, Jae Min Lee
doaj   +1 more source

INTERSTITIAL KERATITIS AND SYNOVITIS, [PDF]

The Lancet, 1895
n ...
openaire   +1 more source

Spontaneous Synovitis in Wistar Rats

, 1998
Spontaneous synovitis has been detected in the stifle joints of control Wistar rats in 4-wk and 2-yr toxicity studies, and a specific site was found to be predisposed to synovitis.
Ikuo Mori, Hitoshi Kandori, Hisashi Anayama, Hirofumi Nagai, Satoshi Sasaki   +4 more
core   +1 more source

Radiosynovectomy in Hemophilic Synovitis

Malecular Imaging and Radionuclide Therapy, 2014
Radisosynovectomy (RS) is a local form of radionuclide therapy used in various forms of arthritis characterized by synovitis. In hemophilic arthropathy, RS provides removal of inflamed synovium and prevents further joint damage. This review focuses on the practical aspects of radionuclide synovectomy in hemophilic patients and describes the issues both
openaire   +3 more sources

Neuroendocrine - immune interactions in synovitis

, 2007
Synovial tissue lines the noncartilaginous surfaces of synovial joints and supplies these avascular structures with nutrients. In diseases such as rheumatoid arthritis, inflammation of the synovial tissue - synovitis induces diffuse damage to the joints.
Johannes WJ Bijlsma, Maurizio Cutolo, Rainer H Straub, Straub, Rainer H, Bijlsma, Johannes Wj, Straub, Rainer H., Cutolo, Maurizio   +6 more
core   +1 more source

Pathogenesis and treatment options for hemophilic synovitis [PDF]

, 2017
INTRODUCTION: Hemophilia is characterized by recurrent bleeding episodes, most commonly in the knees, elbows and ankles. Repeated hemarthroses lead to synovial hypertrophy and a vicious cycle of chronic synovitis arises, leading to destruction of the ...
Carlos Rodriguez-Merchan, E, Liddle, Alexander D, Liddle, AD   +2 more
core   +1 more source

Validation of International Classification of Diseases Code–Based Case Definitions of Immune Checkpoint Inhibitor–Associated Inflammatory Arthritis From Administrative Health Data

Arthritis &Rheumatology, EarlyView.
Objective Immune checkpoint inhibitors (ICIs) for cancer can lead to immune‐related adverse events, including ICI‐associated inflammatory arthritis (ICI‐IA). There are no validated International Classification of Diseases (ICD) code–based case definitions for ICI‐IA.
Manar Elsayed, Zoe Hsu, Finlay A. McAlister, William D. Leslie, Lisa M. Lix, Sasha Bernatsky, Suzanne N. Morin, Michelle M. Graham, Aurore Fifi‐Mah, Shahin Jamal, Janet Roberts, Carrie Ye   +11 more
wiley   +1 more source

Histological synovitis and radiographic damage in knee osteoarthritis: insights from a comprehensive analysis of ultrasound-guided synovial biopsies in 161 patients

RMD Open
Objective Synovial inflammation plays a crucial role in osteoarthritis (OA) by producing key cytokines that mediate synovium–cartilage interaction and drive damage progression.
Maria-Antonietta D’Agostino, Barbara Tolusso, Stefano Alivernini, Marco Gessi, Pietro Rubortone, Enrico De Lorenzis, Dario Bruno, Marco Maria Lizzio, Flavia Leone   +8 more
doaj   +1 more source

The Potential Role of Synovial T Cell Infiltration Following Knee Joint Injury in Symptoms and Progression to Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Identification of osteoarthritis (OA)–specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi, Miriam T. Jackson, Cindy C. Shu, Susan M. Smith, Margaret M. Smith, Sanaa Zaki, Hadrian Platzer, Nils Rosshirt, David Giangreco, Carla R. Scanzello, Christopher B. Little   +10 more
wiley   +1 more source